ID   M4S7Q9_9SPHN            Unreviewed;       424 AA.
AC   M4S7Q9;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Putative efflux pump {ECO:0000313|EMBL:AGH51786.1};
GN   ORFNames=G432_20520 {ECO:0000313|EMBL:AGH51786.1};
OS   Sphingomonas sp. MM-1.
OG   Plasmid pISP1 {ECO:0000313|EMBL:AGH51786.1,
OG   ECO:0000313|Proteomes:UP000011816}.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=745310 {ECO:0000313|EMBL:AGH51786.1, ECO:0000313|Proteomes:UP000011816};
RN   [1] {ECO:0000313|EMBL:AGH51786.1, ECO:0000313|Proteomes:UP000011816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MM-1 {ECO:0000313|EMBL:AGH51786.1};
RC   PLASMID=Plasmid pISP1 {ECO:0000313|Proteomes:UP000011816};
RX   PubMed=23682148;
RA   Tabata M., Ohtsubo Y., Ohhata S., Tsuda M., Nagata Y.;
RT   "Complete Genome Sequence of the gamma-Hexachlorocyclohexane-Degrading
RT   Bacterium Sphingomonas sp. Strain MM-1.";
RL   Genome Announc. 1:E00247-13(2013).
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DR   EMBL; CP004038; AGH51786.1; -; Genomic_DNA.
DR   AlphaFoldDB; M4S7Q9; -.
DR   KEGG; sphm:G432_20520; -.
DR   PATRIC; fig|745310.14.peg.4260; -.
DR   HOGENOM; CLU_002755_2_0_5; -.
DR   Proteomes; UP000011816; Plasmid pISP1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF10; EFFLUX PUMP MEMBRANE TRANSPORTER; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Plasmid {ECO:0000313|EMBL:AGH51786.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011816};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        247..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        345..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        374..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   424 AA;  45096 MW;  EE9EFF73527A768B CRC64;
     MMFTMLKPWE ERSGEENSSL ALVGKAMGFF TSIKEAMVFA LNPPAIAELG IAGGFTFKLE
     DVGGNGAEAL FNARNQLLAA ASQSPILAGV RPEGQEDAPQ LRVMIDRIQA RALGLSIGDV
     NGTLAIAFGS AYANDFNREG RILRVLLQAE ASHRMTPQDV LDLKVRNAAG EMVPFGSFTQ
     VEWTSGAQQL QRYNGYPSMT ISGNAAPGQS TGEAMAEMER LANALPEGFA YEWTGMSYEE
     QQAGGQVGML LGLSILVVFL LLAALYESWS IPVSVLLVVP LGVLGSVLFT VMRGLSADVY
     FNVGIITIIG LAAKNAILIV EFAIEQEAEG KTPLEATLEA VKLRLRPIIM TSLAFIGGMI
     PLFIASGAGA ASRIAVGTGV VGGMLAATVL GIFFIPLFYL SIRRWLSKKR PAAPGQAQPE
     PNHA
//