ID M4SBP1_9SPHN Unreviewed; 334 AA.
AC M4SBP1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component {ECO:0000313|EMBL:AGH48072.1};
GN ORFNames=G432_01720 {ECO:0000313|EMBL:AGH48072.1};
OS Sphingomonas sp. MM-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=745310 {ECO:0000313|EMBL:AGH48072.1, ECO:0000313|Proteomes:UP000011816};
RN [1] {ECO:0000313|EMBL:AGH48072.1, ECO:0000313|Proteomes:UP000011816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MM-1 {ECO:0000313|EMBL:AGH48072.1};
RX PubMed=23682148;
RA Tabata M., Ohtsubo Y., Ohhata S., Tsuda M., Nagata Y.;
RT "Complete Genome Sequence of the gamma-Hexachlorocyclohexane-Degrading
RT Bacterium Sphingomonas sp. Strain MM-1.";
RL Genome Announc. 1:E00247-13(2013).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP004036; AGH48072.1; -; Genomic_DNA.
DR AlphaFoldDB; M4SBP1; -.
DR STRING; 745310.G432_01720; -.
DR KEGG; sphm:G432_01720; -.
DR PATRIC; fig|745310.14.peg.352; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_5; -.
DR Proteomes; UP000011816; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011816}.
FT DOMAIN 1..176
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 334 AA; 36320 MW; 26AE32BFB41A6BFC CRC64;
MNMIQAINSA LDVMMARDSD IVVMGEDVGY FGGVFKATEG LQAKHGKTRV FDTPITECGI
IGVAVGMCTY GLRPVPEIQF ADYIYPALDQ IVSEAARLRY RSAGEFTAPI TVRSPFGGGI
FGGQTHSQSP EGIFTHVAGL KTVIPSNPYD AKGLLIAAIE DNDPVIFFEP KRIYNGPFDG
NYDRPVTPWS KHPTSAVPEG YYKVPLGKAA VVRPGNDVTV LAYGTMVHVA AAVIEEKGID
AELIDLRTLV PLDIETITES VKKTGRCVVV HEATKTSGFG AELSALVQEH CFHHLEAPVQ
RVTGWDTPYP HSLEWAYFPG PVRLGEALKR VMQD
//
