ID M4X0E7_9PSED Unreviewed; 347 AA.
AC M4X0E7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=2-oxoisovalerate dehydrogenase subunit beta {ECO:0000313|EMBL:AGI24472.1};
GN ORFNames=H681_13010 {ECO:0000313|EMBL:AGI24472.1};
OS Pseudomonas sp. ATCC 13867.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1294143 {ECO:0000313|EMBL:AGI24472.1, ECO:0000313|Proteomes:UP000012082};
RN [1] {ECO:0000313|EMBL:AGI24472.1, ECO:0000313|Proteomes:UP000012082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13867 {ECO:0000313|EMBL:AGI24472.1,
RC ECO:0000313|Proteomes:UP000012082};
RX PubMed=23723394;
RA Ainala S.K., Somasundar A., Park S.;
RT "Complete genome sequence of Pseudomonas denitrificans ATCC 13867.";
RL Genome Announc. 1:E00257-E00213(2013).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP004143; AGI24472.1; -; Genomic_DNA.
DR AlphaFoldDB; M4X0E7; -.
DR STRING; 1294143.H681_13010; -.
DR KEGG; pdr:H681_13010; -.
DR PATRIC; fig|1294143.3.peg.2622; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_6; -.
DR Proteomes; UP000012082; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 14..189
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 347 AA; 38135 MW; 2547D823AA3479E6 CRC64;
MNPQHENAQA VTSMTMIQAL RSAMDVMLER DDNVVVFGQD VGYFGGVFRC TEGLQKKYGT
SRVFDAPISE SGIIGAAVGM CAYGLRPVVE IQFADYVYPA TDQLVSEAAR IRYRSVGDFV
VPMVVRMPCG GGIYGGQTHS QSPEAMFTQV CGLRTVMPSN PYDAKGLLIA CIENDDPVIF
LEPKRLYNGP FDGHHDRPVT PWSKHPASQV PEGYYSVPLD KAVIARPGSE LTVLTYGTTV
YVAQTAAEET GVDAEIIDLR SLWPLDLDTI VESVKKTGRC VIVHEATRTC GYGAELMSLV
QENCFHHLES PIVRVTGWDT PYPHAQEWDY FPGPARVGAA FKRAMEV
//
