ID   M4YJP4_THEXX            Unreviewed;       461 AA.
AC   M4YJP4;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=NAD-dependent aldehyde dehydrogenase {ECO:0000313|EMBL:AGI47265.1};
GN   ORFNames=TALC_00254 {ECO:0000313|EMBL:AGI47265.1};
OS   Thermoplasmatales archaeon (strain BRNA1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales.
OX   NCBI_TaxID=1054217 {ECO:0000313|EMBL:AGI47265.1, ECO:0000313|Proteomes:UP000012076};
RN   [1] {ECO:0000313|EMBL:AGI47265.1, ECO:0000313|Proteomes:UP000012076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRNA1 {ECO:0000313|EMBL:AGI47265.1,
RC   ECO:0000313|Proteomes:UP000012076};
RA   Denman S.E., Evans P., Bragg L., Padmanahba J., McKenzie M., Edwards D.,
RA   Krzycki J., McSweeney C., Morrison M.;
RT   "Thermoplasmatales-like gut symbionts are pyrrolysine dependent-
RT   methanogens.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002916; AGI47265.1; -; Genomic_DNA.
DR   AlphaFoldDB; M4YJP4; -.
DR   STRING; 1054217.TALC_00254; -.
DR   KEGG; tar:TALC_00254; -.
DR   eggNOG; arCOG01252; Archaea.
DR   HOGENOM; CLU_005391_5_1_2; -.
DR   Proteomes; UP000012076; Chromosome.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000012076}.
FT   DOMAIN          53..443
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   461 AA;  49746 MW;  CCDDEB6D465646CE CRC64;
     MSDRIFDDSK FDAAYDQALD SPKHDFPSKI NGENVASGIE DLLVSPVDDT IIFGRLQDPV
     PGTMKKAAED AARAFEMWSK SSPEERSRIL SAVADSIEKR LYRLAADVVL STGMVRKDAF
     AEAETCLEVV RQASKDAMNV KGKPRGVWGI IALESSPLAS VIGYSAAAIA AGNTVVMMPS
     GHCPRPVYAV FDLFEQAGLP DGVLNLVCDR TDRFATELSD DENVAGVVAS GCGKAMDDMI
     FLAVDDTLGY INEVKGMNPI VVSQPGDIKK AADSIIDSAF QNNGKGLYAT SKVIVSADDD
     RELTKAIVER LKDLNVNDPG EKECQMGPLM NKEEEKRLTG LLDSEAAYVV MGGKRVKKEY
     TENGLYYTPI LLTSVDPDDD IQYVDSGLPI LVIKQAAGAD AILQELDQTD CGLSVGVISS
     DSKLISKIKE FADEENLQVF VNTSSRSLKA ASKARAENFT V
//