ID M4YLU2_THEXX Unreviewed; 391 AA.
AC M4YLU2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Pyruvate:ferredoxin oxidoreductase-related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit {ECO:0000313|EMBL:AGI48154.1};
DE EC=1.2.7.1 {ECO:0000313|EMBL:AGI48154.1};
GN ORFNames=TALC_01166 {ECO:0000313|EMBL:AGI48154.1};
OS Thermoplasmatales archaeon (strain BRNA1).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales.
OX NCBI_TaxID=1054217 {ECO:0000313|EMBL:AGI48154.1, ECO:0000313|Proteomes:UP000012076};
RN [1] {ECO:0000313|EMBL:AGI48154.1, ECO:0000313|Proteomes:UP000012076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRNA1 {ECO:0000313|EMBL:AGI48154.1,
RC ECO:0000313|Proteomes:UP000012076};
RA Denman S.E., Evans P., Bragg L., Padmanahba J., McKenzie M., Edwards D.,
RA Krzycki J., McSweeney C., Morrison M.;
RT "Thermoplasmatales-like gut symbionts are pyrrolysine dependent-
RT methanogens.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC chain. {ECO:0000256|ARBA:ARBA00011595}.
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DR EMBL; CP002916; AGI48154.1; -; Genomic_DNA.
DR AlphaFoldDB; M4YLU2; -.
DR STRING; 1054217.TALC_01166; -.
DR KEGG; tar:TALC_01166; -.
DR PATRIC; fig|1054217.5.peg.1109; -.
DR eggNOG; arCOG01608; Archaea.
DR HOGENOM; CLU_002569_5_0_2; -.
DR Proteomes; UP000012076; Chromosome.
DR GO; GO:0019164; F:pyruvate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:AGI48154.1};
KW Pyruvate {ECO:0000313|EMBL:AGI48154.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000012076}.
FT DOMAIN 21..244
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 266..368
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 391 AA; 43000 MW; 4F9F03DF01CB5965 CRC64;
MSSKVGTDIA INGDGAVALA WKQINPDVVA AYPITPQTII VEDFSKYVAN GEVDTEFIDV
ESEHSALTLC STSSSAGART FTATASQGLA YMWEMLPITA AMRVPVMMAV ANRTVSGPIN
INNDHGDVMS ARDTGWLSIF AENVQEAYDM SIIGPRIAEH HEVQLPILVN LDGFILTHAI
ERMTPLDTQH VRDFVGEFKP LYPLLDTDHP VTHNLMDGPL FYFPHKYQMV VAMNKALDVA
REVFAEFAKI SGREYHMVEE YRCDDADYIA IVLGSSFGTM KQAVDNLRDE GMKVGVAMPR
VYRPWPADEI AALCKGKKAV IVMDRHLSIG AYGPMFPEVC ASIAVNGKMP EMYNFIYGLG
GADTMVSDFM SVYKTVEAGK ANTINYLGVK E
//
