ID   M4YN12_THEXX            Unreviewed;       343 AA.
AC   M4YN12;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Hydrogenase expression/formation protein HypE {ECO:0000313|EMBL:AGI48465.1};
GN   ORFNames=TALC_01492 {ECO:0000313|EMBL:AGI48465.1};
OS   Thermoplasmatales archaeon (strain BRNA1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales.
OX   NCBI_TaxID=1054217 {ECO:0000313|EMBL:AGI48465.1, ECO:0000313|Proteomes:UP000012076};
RN   [1] {ECO:0000313|EMBL:AGI48465.1, ECO:0000313|Proteomes:UP000012076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRNA1 {ECO:0000313|EMBL:AGI48465.1,
RC   ECO:0000313|Proteomes:UP000012076};
RA   Denman S.E., Evans P., Bragg L., Padmanahba J., McKenzie M., Edwards D.,
RA   Krzycki J., McSweeney C., Morrison M.;
RT   "Thermoplasmatales-like gut symbionts are pyrrolysine dependent-
RT   methanogens.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HypE family.
CC       {ECO:0000256|ARBA:ARBA00006243}.
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DR   EMBL; CP002916; AGI48465.1; -; Genomic_DNA.
DR   AlphaFoldDB; M4YN12; -.
DR   STRING; 1054217.TALC_01492; -.
DR   KEGG; tar:TALC_01492; -.
DR   PATRIC; fig|1054217.5.peg.1420; -.
DR   eggNOG; arCOG00636; Archaea.
DR   HOGENOM; CLU_049733_0_0_2; -.
DR   Proteomes; UP000012076; Chromosome.
DR   CDD; cd02197; HypE; 1.
DR   Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR   Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR   InterPro; IPR011854; HypE.
DR   InterPro; IPR010918; PurM-like_C_dom.
DR   InterPro; IPR036676; PurM-like_C_sf.
DR   InterPro; IPR016188; PurM-like_N.
DR   InterPro; IPR036921; PurM-like_N_sf.
DR   NCBIfam; TIGR02124; hypE; 1.
DR   PANTHER; PTHR30303:SF0; CARBAMOYL DEHYDRATASE HYPE; 1.
DR   PANTHER; PTHR30303; HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPE; 1.
DR   Pfam; PF00586; AIRS; 1.
DR   Pfam; PF02769; AIRS_C; 1.
DR   PIRSF; PIRSF005644; Hdrgns_mtr_HypE; 1.
DR   SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR   SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000012076}.
FT   DOMAIN          35..141
FT                   /note="PurM-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00586"
FT   DOMAIN          171..317
FT                   /note="PurM-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02769"
SQ   SEQUENCE   343 AA;  36299 MW;  DE5EE31A3815FB73 CRC64;
     MNDGAGGELM QEFISKHITS HFPKMTAEVP LDSLDDSAVV DDVVFTIDGH TVQPLFFPGG
     DIGRIAVSGT INDISVMGAK PIGLASSVIL EEGLDSDTVD KVMASMGKTA GDAGVPIVTG
     DTKVMGAGEI DKMVITTSAI GKRWDALDHD MEVANSYRKV DSRWCADSNT RPGDVIIVSG
     YVGDHGVSLL SFREGYGFES DVKSDVQPLN KMIERGLRVG GIVAMKDPTR GGLANTLNEW
     ADKSKCQLDI NEADIPLRDG VVSACELLGI EPLNIGNEGK CVISVVPEMA EEVLKAIRAT
     PEGKDAAIIG RASEGPSRVV LKTEVGGRRI LEPPSGDPVP RIC
//