ID M5BRB2_THACB Unreviewed; 1293 AA.
AC M5BRB2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Vacuolar import and degradation protein 21 {ECO:0000256|ARBA:ARBA00029670};
GN ORFNames=BN14_03734 {ECO:0000313|EMBL:CCO29716.1};
OS Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom
OS rot fungus) (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=1108050 {ECO:0000313|EMBL:CCO29716.1, ECO:0000313|Proteomes:UP000012065};
RN [1] {ECO:0000313|EMBL:CCO29716.1, ECO:0000313|Proteomes:UP000012065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG1-IB / isolate 7/3/14 {ECO:0000313|Proteomes:UP000012065};
RX PubMed=23280342; DOI=10.1016/j.jbiotec.2012.12.010;
RA Wibberg D.W., Jelonek L.J., Rupp O.R., Hennig M.H., Eikmeyer F.E.,
RA Goesmann A.G., Hartmann A.H., Borriss R.B., Grosch R.G., Puehler A.P.,
RA Schlueter A.S.;
RT "Establishment and interpretation of the genome sequence of the
RT phytopathogenic fungus Rhizoctonia solani AG1-IB isolate 7/3/14.";
RL J. Biotechnol. 0:0-0(2013).
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. {ECO:0000256|ARBA:ARBA00025178}.
CC -!- SIMILARITY: Belongs to the EAF1 family.
CC {ECO:0000256|ARBA:ARBA00008913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO29716.1}.
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DR EMBL; CAOJ01005327; CCO29716.1; -; Genomic_DNA.
DR HOGENOM; CLU_262918_0_0_1; -.
DR Proteomes; UP000012065; Unassembled WGS sequence.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:UniProt.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR014012; HSA_dom.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR46459:SF1; E1A-BINDING PROTEIN P400; 1.
DR PANTHER; PTHR46459; E1A-BINDING PROTEIN P400-RELATED; 1.
DR Pfam; PF07529; HSA; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR SMART; SM00573; HSA; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51204; HSA; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204}.
FT DOMAIN 474..547
FT /note="HSA"
FT /evidence="ECO:0000259|PROSITE:PS51204"
FT DOMAIN 885..944
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 87..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 857..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..984
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1246..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..272
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..641
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1140..1154
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1155..1199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1246..1274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1293 AA; 142187 MW; C81C60337A0D1366 CRC64;
MTAAADARNS LLSRKSAEKE ASALNRERLI RELLRATEWR SKSGVGAFPR VSGQDVVPDE
LLHYYLTPFP DGTFPSVLDL VTRHMEPTPE PELEPVDSLE IQPLSDPEPL PEFEPENESE
LDPVVELGTP IVKTEEDDAV MNDSDDVAPQ DQDEDVEMHP PMETPSETAT ATATAEATPD
PLPFASEPTS PLVQVHTSTQ PIQLPVQPSV QVPPIITQLP PELAALPSGT IAEPIEEPNP
NQEPTPARPK FDPSRPLHTQ PPLAPPPPDE RLPTIATLKD LMFSTSSSAT ELEPTINPSA
LSIRQSPTTP TAKTNPSPKS LTNPYTASLP PLPPLPADLA RKVAGVKARR QRVQQTNGVN
WGGNGIWTGQ PQQPQQAGAS GLGPGGAGAQ GWWASVSVGQ APAPGQTHAP QPGMELLRWQ
AILQINPAHV FARRPTKELM SRRKKVLRHE LEYTRAMQRI EQLKQDGMWS FRQPKKQRGP
ALPKTHWDYL MDEMKWLQID YREERRWKTA VAFEIAHAVR EWHEATPEER KEMCVGFRKV
DHQMDEEGGE EEGDDVEMDE GKGAAEGERV EKDVEMDEQT GSDGKAVELR SEPENEDDPE
EGQEPHTGGM DPQDNVMGAD DDVVVVEEAT SPEKENEGDQ EPGVLPDDDV PGALTKEEPA
DPPSNELSPT KDPDLPDDDA DGEDDPSLLA KTALRPDAEG AEATLADLEY IDSVREELVQ
LATAPSLMTS FALPPLPIPT STKTKPDSID ALAELFPDLS LYTGLSDLID EDPAKQEKRP
DESMTSVASG KLAHASRLMD IKPVLVGALD PARHLFKNRW IGLDEVPAVE DSKDVGTVRQ
DTLFTGNYLF AADRKPEEKA LRRRPDSGMT HPVPAHVPLP PRDTQARVER VTWTPEDDQL
LKSICDAYPN SWTLTADLFN SSRVTIKPDV RTAWDCYDRY NKMFGGGTAG GEDKPQGQGP
VEIALPSPGG TVRKDSKPPM LDNKGKKVFE NKKQVRQHYL YDTLRKVVRK RENANKANQP
PKRTIPPPHE THSQLSSGQR IYTPAELSKL KAERDARHYA EMIKRRQEIY QQAVAAGRPV
PRMPPGLVNI PIRNAQMNAH VQMQLQQQQA QVQAQQSQTQ QSPPNQQAQP QVAQTQPQTP
ALPPVQPQAQ TPQPTPGQPQ VQATGFVQRP QLVQSSQQQM SPPNGQAQPP RTQPQQQAMS
HLLRQQMHMM PGTGIQNGMF VNRAQMGPEQ MNQLLLQQAA RALQNQQQTT AATQPQISAQ
PQLQVPGIQP NPTVAPTASP TPAAAGDGDV TMQ
//
