ID M5BTQ9_THACB Unreviewed; 1199 AA.
AC M5BTQ9;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Mitogen-activated protein kinase organizer 1 {ECO:0000313|EMBL:CCO27107.1};
DE EC=2.3.2.2 {ECO:0000313|EMBL:CCO27107.1};
GN ORFNames=BN14_01141 {ECO:0000313|EMBL:CCO27107.1};
OS Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom
OS rot fungus) (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=1108050 {ECO:0000313|EMBL:CCO27107.1, ECO:0000313|Proteomes:UP000012065};
RN [1] {ECO:0000313|EMBL:CCO27107.1, ECO:0000313|Proteomes:UP000012065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG1-IB / isolate 7/3/14 {ECO:0000313|Proteomes:UP000012065};
RX PubMed=23280342; DOI=10.1016/j.jbiotec.2012.12.010;
RA Wibberg D.W., Jelonek L.J., Rupp O.R., Hennig M.H., Eikmeyer F.E.,
RA Goesmann A.G., Hartmann A.H., Borriss R.B., Grosch R.G., Puehler A.P.,
RA Schlueter A.S.;
RT "Establishment and interpretation of the genome sequence of the
RT phytopathogenic fungus Rhizoctonia solani AG1-IB isolate 7/3/14.";
RL J. Biotechnol. 0:0-0(2013).
CC -!- PATHWAY: Sulfur metabolism; glutathione metabolism.
CC {ECO:0000256|ARBA:ARBA00005115}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO27107.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAOJ01001508; CCO27107.1; -; Genomic_DNA.
DR AlphaFoldDB; M5BTQ9; -.
DR HOGENOM; CLU_270970_0_0_1; -.
DR Proteomes; UP000012065; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0036374; F:glutathione hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0103068; F:leukotriene C4 gamma-glutamyl transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.246.130; -; 1.
DR Gene3D; 3.60.20.40; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR043138; GGT_lsub_C.
DR InterPro; IPR000101; GGT_peptidase.
DR InterPro; IPR043137; GGT_ssub.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR11686; GAMMA GLUTAMYL TRANSPEPTIDASE; 1.
DR PANTHER; PTHR11686:SF9; GLUTATHIONE HYDROLASE 7; 1.
DR Pfam; PF01019; G_glu_transpept; 2.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:CCO27107.1}; Kinase {ECO:0000313|EMBL:CCO27107.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCO27107.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 129..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 909..951
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 952..993
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 994..1035
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1184..1199
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 17..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..605
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..696
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..725
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..768
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 391
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR600101-1"
SQ SEQUENCE 1199 AA; 128822 MW; ACE0A467CC49C39D CRC64;
MAAGAVKPAV SYAAVVAKGT SASSHHDPDS PTHSSPERAG PKGKARDSRV NFADSSAPNE
RTALLRQQRS SGSGHEGNGE QSNNDNDEDR GFVARAKRAL GFGKGERDTL PLYAEDGHTQ
RPVRLSGGLG ALLGLILIAV LVAGALLVRS GDHDTGPSPN PPTPAYPIPS GGTSGPRNPA
YLIKADHGAV ASEAKVCSQI GVDVLKDGGN AIDAAIASNL CVGTVNPFSA GIGGGGFMGS
IAASLISKIQ ATGGIMTLED LESYKVVERP ALKSIYQGRH VYTTHAPSSG PVLIHVLNAL
ERFGSGPNVH DQVAMQKEGG LWWHRVTEAL KFGSAARTRL GDPAFGNNHK LMAEIPTKNF
GKNVSSRITD DTTHAPDYYN PVYDVQIDHG TTHTSAADAE GFAIALTSSV NLIWGSRVMD
PATGVILNDV MDDFSTPGLP NAFGLWPSPW NYPEAGKRQV SSMAPTIMEH ASGNFYLALG
GSGGSRIFGA IIQAAVNLDR GMNISGAIEA PRVHDQLFPT LVSIESGFGD KEIEALKQRG
HNTSVFDINL GVAEIQAVTQ DEDGHISGEW QRLEDDDDHE RQGLTGQRRW KGKSKEVDYP
DTGLTSIDEE RAQVDGASKS YPPLSDDVAE EREVAENLKR WENAERLRRK AARESKTHST
SSVPNPLTEL TRRASQALFR RSTGSGRGSV TILRTDSPTA LDDLERGSAQ LSRAHTDSTP
RNPFRDSAGV ASDVALVSPA TADPFKPSGS PKERQRSDST STITGGITPV QPIPKRPTLE
TLESSFLGSQ DRGQAPTPRP IDLPSTPAPQ HAYEGGGAVP ARMSGPEGMR IRRSAAYVQE
EEEELEREKR DGRWWTDWLC GLKERRDPSG QTHVTRLLSL VLTTIFMSQK PARQQKQPAS
APRKLHCKLE NHRGPVHVAT YAKGEAKYLL TGGQDRTIRL WNPDSGSEIK KYEGHGYEVL
SISVAHDNAR FASGGGDRSV YLWNVTAGVT ERRMPGHLGK INAVAFNADA SVLASGSYDS
SVRLWDLKAQ NRTPIQVLGE AKDSITCIHI GAAEVITGSV DGHVRTYDIR MGELKSDFIG
PPISSISLST DNQTLLVCTL DSKLRLMDRA NGQMLNTFSG HVSNDYRTHA CFGYGEGSVL
CGDEQGKIWE WDLLDAKAVA PDPPKVHDKV ITWVEHHPLA AGEMVSASAD GVVKVWRAE
//
