ID M5CE34_THACB Unreviewed; 1293 AA.
AC M5CE34;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Putative RNA-directed DNA polymerase from transposon X-element {ECO:0000313|EMBL:CCO34112.1};
DE EC=2.7.7.49 {ECO:0000313|EMBL:CCO34112.1};
GN Name=ORF2 {ECO:0000313|EMBL:CCO34112.1};
GN ORFNames=BN14_08204 {ECO:0000313|EMBL:CCO34112.1}, RSOLAG1IB_10459
GN {ECO:0000313|EMBL:CEL62418.1};
OS Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) (Lettuce bottom
OS rot fungus) (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=1108050 {ECO:0000313|EMBL:CCO34112.1, ECO:0000313|Proteomes:UP000012065};
RN [1] {ECO:0000313|EMBL:CCO34112.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Isolate 7/3/14 {ECO:0000313|EMBL:CCO34112.1};
RA Jelonek L.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCO34112.1, ECO:0000313|Proteomes:UP000012065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG1-IB / isolate 7/3/14 {ECO:0000313|Proteomes:UP000012065},
RC and Isolate 7/3/14 {ECO:0000313|EMBL:CCO34112.1};
RX PubMed=23280342; DOI=10.1016/j.jbiotec.2012.12.010;
RA Wibberg D.W., Jelonek L.J., Rupp O.R., Hennig M.H., Eikmeyer F.E.,
RA Goesmann A.G., Hartmann A.H., Borriss R.B., Grosch R.G., Puehler A.P.,
RA Schlueter A.S.;
RT "Establishment and interpretation of the genome sequence of the
RT phytopathogenic fungus Rhizoctonia solani AG1-IB isolate 7/3/14.";
RL J. Biotechnol. 0:0-0(2013).
RN [3] {ECO:0000313|EMBL:CEL62418.1, ECO:0000313|Proteomes:UP000059188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rhizoctonia solani AG1-IB 7/3/14 {ECO:0000313|EMBL:CEL62418.1};
RA Wibberg Daniel;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CAOJ01012627; CCO34112.1; -; Genomic_DNA.
DR EMBL; LN679168; CEL62418.1; -; Genomic_DNA.
DR STRING; 1108050.M5CE34; -.
DR HOGENOM; CLU_000680_23_3_1; -.
DR Proteomes; UP000012065; Unassembled WGS sequence.
DR Proteomes; UP000059188; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF00075; RNase_H; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:CCO34112.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000059188};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:CCO34112.1};
KW Transferase {ECO:0000313|EMBL:CCO34112.1}.
FT DOMAIN 505..784
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 983..1125
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 393..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1293 AA; 143172 MW; 6FAFBBEAD3E0108D CRC64;
MIAQLHAPDL SSFSIWQLNV NKSNEAQTAF AHDPDARSAT IVAIQEPYLD HLGGSRAPPG
WTPIYPSNHH KKDQPRSRSF LAVNPCLSSN VWEQVPCPSP DVTAMKVQTP LGSILICNIY
NPCDDNAPLP HVSTLLRAHR GHKIVLGDFN RHHPDWDEPR NAHLFTSAAL DLAQPLLDLV
SKDLLSMLLP RDLPTLQSTS SKNYTRPDNV FASALLVESL VSCNTIPASR PPCTDHFPIA
TVLDFSATQA PNVTKPNFKK TDWCLFRQAL SEKLELLPGL RRIGSQEEID QRAGDLTKII
NEAVQASTPV LKLCARSKRW WSPELGAHRN LSRTLSTRSY RARTDPEDPV HEEYRRQRNR
YSQAIKDAKR KHWEGYLEEL DEESMWTAAR YLSSEPTDGG RTRVPSLRHT NPDGTPASAS
DNDGKSHMLM ESFFPPAPTP PRVNAPTPVH PTPVEDLPEI QTSHIRQVVY AMKPHKAPGP
DGLPACVYIN SIDLLDKHLL PIFRASLRLG IYPATWRESR TVVLRKPGKP DYSIAKAYRP
IALLNVISKI LSSCMATRLN SLAEEHGWLP DHHFGGRPGR TTTDALHLLA KTIKDAWATK
KVASALFLDV KGAFPHAYPP RLAENMRNLG VPTVYVNWML AKLSGRTTCL AFDDYTSTPL
PIDNGIDQGC PLSVIFYLLY NAPLVKVPRP LRNELCVAYI DDITFVVWGP SFEANHCALV
NMMTRRGGAL DWSDTHNSTF ELDKTACIDF APPATSKKLD RPPLTIRDQV ITPVKSHTLL
GVIMDQTLSW REQCDKALAK GQQWAGQLNR LARMSYGAPI RTARRLYLSI AVPRFSYAAD
VWYTPVSQGV GGRRTGSAGF ADRLARIQST AARAILGAMR SNPVTSLDAH LDLLPMYLLM
NEACQRAAIR LAATPSDHPL HKAVIKCATG RKKHQPPLQR ILHFAGVNPA NFEQWPFDRK
PLPSVPPEEF QDRHVATASA WADRSHLLVF ADAAVSRAGV AAAAILWGDG NRELRTGLRL
GEPGSFSSLD AELAGIMLAA HLVATIQGDT IVDDVTIYSD SQAAIACINH RTEGASRKLL
KATRKAIEVA RKGSGGTTIN LRWCPGHTGV PGIEEADAEA SRVASGHTHP PHLIPKFLAD
FHPATNPSTF KQSMKAENKK LAEAHWSSSA AGAKFATKYP GLFPRHFLVH TQNLSRSKAT
LLYRLITGHV QLRQHLHRLQ LVDTPQCDLC GLEPETVTHF LFRCSHFAAQ RQLHLSSHGA
DFLRLSYVLH ATPALDPLFD YVKATGRFAD LVR
//
