ID M5DZQ2_9FIRM Unreviewed; 780 AA.
AC M5DZQ2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=PAS domain S-box-containing protein/diguanylate cyclase (GGDEF)-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HSACCH_00885 {ECO:0000313|EMBL:CCU78746.1};
OS Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643.
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=1293054 {ECO:0000313|EMBL:CCU78746.1, ECO:0000313|Proteomes:UP000012063};
RN [1] {ECO:0000313|Proteomes:UP000012063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6643 {ECO:0000313|Proteomes:UP000012063};
RX PubMed=23640197; DOI=10.1128/genomea.00187-13;
RA Kivisto A., Larjo A., Ciranna A., Santala V., Roos C., Karp M.;
RT "Genome Sequence of Halanaerobium saccharolyticum subsp. saccharolyticum
RT Strain DSM 6643T, a Halophilic Hydrogen-Producing Bacterium.";
RL Genome Announc. 1:217-225(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU78746.1}.
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DR EMBL; CAUI01000005; CCU78746.1; -; Genomic_DNA.
DR RefSeq; WP_005488153.1; NZ_CAUI01000005.1.
DR AlphaFoldDB; M5DZQ2; -.
DR STRING; 1293054.HSACCH_00885; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG3437; Bacteria.
DR InParanoid; M5DZQ2; -.
DR OrthoDB; 9805474at2; -.
DR Proteomes; UP000012063; Unassembled WGS sequence.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000012063}.
FT DOMAIN 37..90
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 141..187
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 214..266
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 472..605
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 593..780
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 780 AA; 90586 MW; 9126F2B8FD8313AB CRC64;
MNMKNITDKN IDLKKLLKKL ANQTPGALYQ FNFYPEDETM FCSYISEGVY EIFELYPEEV
LEDVNKVFAR IHPDDKNQIM NSIRESTAQL KLWKETFRVV LPQKGERWIQ GNAKPEKMDD
GCILWHGNLI DISEEKEWKK EIEIYAKALK NISDSVVITD KDFKIEYINK AAKKLFGYSP
DELKGESPGV FNSETHADNI QKKLYKKISR GEVYQGELLY KRKDGSNFIC DMKITPLTNE
NEEIYAYIGI QRDITAKKNK QQEIEFQLKF QKTLSDVSSD LLNINSANID RKINSALKKI
GHFFNIDRSY IFQFSNNYDF VSNTHEWCKK GIEAQIDKLQ NINVNNFSWA MNKLYNNQVI
NIKDIENMDI NKKAEKKLLK ELNLKSIVIM PMHIENELFG FFGFDFVEEK RAFSKDEIRL
LRIFTDFITN AFLKHIDYQK IKELTYHDSL TGLYNRRFFV EELKRLDTKR QLPISIIVAD
IDGLKIINDS FGHQKGDCLI KKSADLIKND IRDEDILARH GGDEFAILLP QTSGEEAENI
VSRIKNNTKK SSSYKFNISI SFGIATKNKI EEDINEIFKL ADDKMYQNKL SENKSIKNKI
VQGLISTLEV KSNETKEHTV RMTKLSLNFA NYLNLSNSEI NRLSLLSNLH DIGKITVDDK
ILKKSEKLTE EEWEAMKKHS EAGYNIANSS EEFALVAEEI YSHHERWDGN GYPRGLKGKE
IPFLARVIFL IDTYDVITSG RPYKKEMSRS EALKEIENCA GSQFDPELAA DFIDFIKEKY
//
