ID M5E151_9FIRM Unreviewed; 513 AA.
AC M5E151;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Na+/H+ antiporter {ECO:0000313|EMBL:CCU79502.1};
GN ORFNames=HSACCH_01383 {ECO:0000313|EMBL:CCU79502.1};
OS Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643.
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=1293054 {ECO:0000313|EMBL:CCU79502.1, ECO:0000313|Proteomes:UP000012063};
RN [1] {ECO:0000313|Proteomes:UP000012063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6643 {ECO:0000313|Proteomes:UP000012063};
RX PubMed=23640197; DOI=10.1128/genomea.00187-13;
RA Kivisto A., Larjo A., Ciranna A., Santala V., Roos C., Karp M.;
RT "Genome Sequence of Halanaerobium saccharolyticum subsp. saccharolyticum
RT Strain DSM 6643T, a Halophilic Hydrogen-Producing Bacterium.";
RL Genome Announc. 1:217-225(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU79502.1}.
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DR EMBL; CAUI01000015; CCU79502.1; -; Genomic_DNA.
DR RefSeq; WP_005488835.1; NZ_CAUI01000015.1.
DR AlphaFoldDB; M5E151; -.
DR STRING; 1293054.HSACCH_01383; -.
DR eggNOG; COG1757; Bacteria.
DR InParanoid; M5E151; -.
DR OrthoDB; 9762978at2; -.
DR Proteomes; UP000012063; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000012063};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 161..475
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 513 AA; 54750 MW; 4968AEC803471628 CRC64;
MESYGIISLL PPLLAIILAW WSKQVVLSLF LGVFAGALIT NAYNPLFAFM HTLDDYILAS
LADSWNAGII LFLLAMGGMI GIINKSGGII AIGEYVAKKA NSVVKTQFAA WLMGVLIFFD
DYANTLIVGN TMRPITDKMK ISREKLAFIV DLTAAAVSSI VPISTWIAFE VGVIKDGFDS
LGLEMNAYGT FVQTIPYRFY SIFALGFALI IIFTAKDYGP MLKAEKRARS TGETLRPGST
PMVSQEMEEI EQPEGESFTF ANSFLPIIGV ILVTLIGLWY NGGGLEAGTS IRDAFGNADA
SIVLLWAAIS GSFIAGILSF AKGILNISET VDGWIDGAKS MFIACLILVL AWSIGSITED
LGTANYLVSI LEGNIIPEIV PLMIFIFSAF IAFTIGSSWG TVAIVMPLAI PLANSIGIPM
LPTIAAVLTA SVMGDHCSPI SDTTIMSSTA SAVDHMDHVS TQMPYALTVG LVAALFGFLP
AGFGFSAVYL LPLGLVVLYL IVSIIGKKAD EVI
//
