ID M5E2S4_9FIRM Unreviewed; 576 AA.
AC M5E2S4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=HSACCH_02341 {ECO:0000313|EMBL:CCU80826.1};
OS Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643.
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=1293054 {ECO:0000313|EMBL:CCU80826.1, ECO:0000313|Proteomes:UP000012063};
RN [1] {ECO:0000313|Proteomes:UP000012063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6643 {ECO:0000313|Proteomes:UP000012063};
RX PubMed=23640197; DOI=10.1128/genomea.00187-13;
RA Kivisto A., Larjo A., Ciranna A., Santala V., Roos C., Karp M.;
RT "Genome Sequence of Halanaerobium saccharolyticum subsp. saccharolyticum
RT Strain DSM 6643T, a Halophilic Hydrogen-Producing Bacterium.";
RL Genome Announc. 1:217-225(2013).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU80826.1}.
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DR EMBL; CAUI01000023; CCU80826.1; -; Genomic_DNA.
DR AlphaFoldDB; M5E2S4; -.
DR STRING; 1293054.HSACCH_02341; -.
DR eggNOG; COG1345; Bacteria.
DR InParanoid; M5E2S4; -.
DR Proteomes; UP000012063; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07196; Flagellin_IN; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:CCU80826.1};
KW Cilium {ECO:0000313|EMBL:CCU80826.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:CCU80826.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000012063};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 8..104
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 318..553
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 509..536
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 576 AA; 62048 MW; 43F863AE38701AE6 CRC64;
MQLDGLATGM DTTAVIDQLV ALEQRPIYNY QQEISELEMT KGAWRDVNSR LDKLEDRTTD
LKLSSTYNSR SASSSDKDIV TATASNDSNE ANYSITVNNV ASTQRISGNR LDDSTTAIKD
LTGFGSIAAE NNIQINGTDI TINDSDTLAD ISNKINDAEA GVNASIVDNH LVLESADTGE
KNQIALVDDN DLFNSLGVLQ TGDNDNSLST NLMEVKDADT ALGLTGSFQI DVEGGTGSGE
IIVDETTTLN DIKSQVDALA LGGDLSASVT DEANGYFSLS ISSSTAGSDI KLSNTGTENI
LSDLAFGNRS YQNELQTAED ANIDINGIEG ITSSTNTFSE AVDGVTFNIN PDAVVNDGID
TASASVSVSK DTGKATDAVK AFVDQYNSVM NFLDGKTDYD EEEEKGAVLQ GDSTAMRLQT
RLRSLVSSKI KDTGDFKTLS SVGIEIDRDG VMSFDKSKFT EALDQSSEEV MSIFNGESDS
DGFDGMAVRM DSYLDQLMQS NTGLIPRRLD FYDTRIDSLN DDIEDVERKV EMTRDRYVEQ
FAAMETAISE MNQQMSWMQS QLSSLAGSTS MLSSNN
//
