ID M5E3R3_9GAMM Unreviewed; 306 AA.
AC M5E3R3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cadmium, cobalt and zinc/H(+)-K(+) antiporter {ECO:0000313|EMBL:CCU72159.1};
GN ORFNames=TOL_1735 {ECO:0000313|EMBL:CCU72159.1};
OS Thalassolituus oleivorans MIL-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Thalassolituus.
OX NCBI_TaxID=1298593 {ECO:0000313|EMBL:CCU72159.1, ECO:0000313|Proteomes:UP000011866};
RN [1] {ECO:0000313|EMBL:CCU72159.1, ECO:0000313|Proteomes:UP000011866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIL-1 {ECO:0000313|EMBL:CCU72159.1,
RC ECO:0000313|Proteomes:UP000011866};
RX PubMed=23599290; DOI=10.1128/genomeA.00141-13;
RA Golyshin P.N., Werner J., Chernikova T.N., Tran H., Ferrer M.,
RA Yakimov M.M., Teeling H., Golyshina O.V.;
RT "Genome Sequence of Thalassolituus oleivorans MIL-1 (DSM 14913T).";
RL Genome Announc. 1:1-3(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HF680312; CCU72159.1; -; Genomic_DNA.
DR AlphaFoldDB; M5E3R3; -.
DR KEGG; tol:TOL_1735; -.
DR PATRIC; fig|1298593.3.peg.1661; -.
DR eggNOG; COG1230; Bacteria.
DR HOGENOM; CLU_013430_0_0_6; -.
DR Proteomes; UP000011866; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR11562; CATION EFFLUX PROTEIN/ ZINC TRANSPORTER; 1.
DR PANTHER; PTHR11562:SF17; LD05335P; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00022906};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011866};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022906};
KW Zinc transport {ECO:0000256|ARBA:ARBA00022906}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 306 AA; 33023 MW; A807B59F380333C3 CRC64;
MSHLHGGPMS SHQHAPIRYG RVFAVGVLLN LAFVLVEAWY GWKGDSLALL ADAGHNLSDV
AGLLLAWAAF GAAKFKPNAR HSYGWRKGSI IASFINATIL LAAMGALAWE AVGRLTTPAG
VDGMTVIIVA AIGLVINSVT AWMFMQGSQQ DLNIRGAFLH MAADALVSAG VVFAGVLYLW
QGWSWLDPVI SILVALVVMI STWSLFRRSL HLLFDGVPDD IDLPAIRAGL QALKGVAAVH
DLHIWAMSTT ENALTAHLLM IDGQSHDDLL SRATDLLESE FGLHHVTLQL EHYEGGAYRE
SENCVD
//
