ID M5EAG2_9FIRM Unreviewed; 600 AA.
AC M5EAG2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=NADH-ubiquinone oxidoreductase chain F {ECO:0000313|EMBL:CCU77730.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:CCU77730.1};
GN ORFNames=HSACCH_00121 {ECO:0000313|EMBL:CCU77730.1};
OS Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643.
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=1293054 {ECO:0000313|EMBL:CCU77730.1, ECO:0000313|Proteomes:UP000012063};
RN [1] {ECO:0000313|Proteomes:UP000012063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6643 {ECO:0000313|Proteomes:UP000012063};
RX PubMed=23640197; DOI=10.1128/genomea.00187-13;
RA Kivisto A., Larjo A., Ciranna A., Santala V., Roos C., Karp M.;
RT "Genome Sequence of Halanaerobium saccharolyticum subsp. saccharolyticum
RT Strain DSM 6643T, a Halophilic Hydrogen-Producing Bacterium.";
RL Genome Announc. 1:217-225(2013).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU77730.1}.
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DR EMBL; CAUI01000005; CCU77730.1; -; Genomic_DNA.
DR RefSeq; WP_005487093.1; NZ_CAUI01000005.1.
DR AlphaFoldDB; M5EAG2; -.
DR STRING; 1293054.HSACCH_00121; -.
DR eggNOG; COG1894; Bacteria.
DR InParanoid; M5EAG2; -.
DR OrthoDB; 9761899at2; -.
DR Proteomes; UP000012063; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd10549; MtMvhB_like; 1.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR000813; 7Fe_ferredoxin.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF14697; Fer4_21; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR PRINTS; PR00354; 7FE8SFRDOXIN.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000313|EMBL:CCU77730.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000012063};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Ubiquinone {ECO:0000313|EMBL:CCU77730.1}.
FT DOMAIN 543..572
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 573..600
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 600 AA; 64743 MW; 6DB1E0B85F4C3B84 CRC64;
MKDTIYRSHV LICTGTGCVS SGAKTIKESL EEELAANDLS NEIKIVETGC HGFCEKGPIM
IVYPEGVFYC ELESDDVAEI VEEHLLKGRT VERLLFKEPM TEKNIPSYQD IDFYKKQQRI
ALANCGQIDP EDINEYIALG GYEAAGKALS EMEPQEVVDT VKDSGLRGRG GGGFPTGLKW
QFAKNSESDK KYLICNADEG DPGAFMDRSI LEGDPHRIIE GMLVGAYAIG ADEGYVYVRA
EYPLAIKRLQ KAIEDAEEYG LLGEDIFSSG FNFKLHIKKG AGAFVCGEET ALMNSIEGKR
GMPTPRPPYP AVRGLWGKPT NINNVETYAN IPYIITEGAE NFSAIGTEGS SGTKVFALTG
KINNTGLVEV PMGTTLNEVI FEIGGGLGEG KKFKAVQTGG PSGGCLPEDY LDLPIDYDSL
LDAGTMMGSG GMVVMDEDSC MVDVAKFFLN FTQSESCGKC TPCREGTKRM LEILTRITEG
EGKDGDIELL LELGEHIKST SLCGLGQSAP NPVISTIRYF RDEYEAHIHD HNCPAGACTD
LASAYVIDEE ACIGCSKCAK VCPVDAISGE IKNPFTIDPD VCIACGACEP ECPVDAISQG
//
