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Database: UniProt
Entry: M5EY18_9RHIZ
LinkDB: M5EY18_9RHIZ
Original site: M5EY18_9RHIZ 
ID   M5EY18_9RHIZ            Unreviewed;       363 AA.
AC   M5EY18;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   08-MAY-2019, entry version 28.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroG {ECO:0000313|EMBL:CCV10012.1};
GN   ORFNames=MESS4_120133 {ECO:0000313|EMBL:CCV10012.1};
OS   Mesorhizobium sp. STM 4661.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=1297570 {ECO:0000313|EMBL:CCV10012.1, ECO:0000313|Proteomes:UP000012181};
RN   [1] {ECO:0000313|EMBL:CCV10012.1, ECO:0000313|Proteomes:UP000012181}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=STM 4661 {ECO:0000313|EMBL:CCV10012.1,
RC   ECO:0000313|Proteomes:UP000012181};
RA   Genoscope - CEA;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCV10012.1}.
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DR   EMBL; CAAF010000004; CCV10012.1; -; Genomic_DNA.
DR   RefSeq; WP_006325700.1; NZ_CAAF010000004.1.
DR   STRING; 1297570.MESS4_120133; -.
DR   EnsemblBacteria; CCV10012; CCV10012; MESS4_120133.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000012181; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000012181};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:CCV10012.1}.
FT   DOMAIN       42    338       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   363 AA;  38521 MW;  BF1BD03990AC6B27 CRC64;
     MLTTTDDLRV KEIRELSTPD QVMREIPRTL TATRTVTASR NAIHAVLTGT DDRLVVIVGP
     CSIHDPVAAV DYASRLAALR ENLSDRLEIV MRVYFEKPRT TVGWKGLIND PDLDGSFNID
     KGLRMARNVL SAVNNLGLPA ATEFLDMATP QYIADLVAWG AIGARTTESQ IHRELASGLS
     CPVGFKNGTD GNLRIAAEAV KSAAQPHHFM AVTKGGRSAI ATTTGNEDCH VILRGGIQPN
     YDAASIAAAS AELGRIGVAS RLMIDVSHAN SSKKPENQPK VAADVAGQVA TGDERIIGVM
     IESNLVAGRQ DVVPGKPLVH GQSITDGCID WATTEAVLHG LADAVEQRRS ARNAMAASRP
     GAA
//
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