ID M5FU01_DACPD Unreviewed; 350 AA.
AC M5FU01;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=NADP-binding protein {ECO:0000313|EMBL:EJT99638.1};
GN ORFNames=DACRYDRAFT_117835 {ECO:0000313|EMBL:EJT99638.1};
OS Dacryopinax primogenitus (strain DJM 731) (Brown rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Dacryopinax.
OX NCBI_TaxID=1858805 {ECO:0000313|EMBL:EJT99638.1, ECO:0000313|Proteomes:UP000030653};
RN [1] {ECO:0000313|EMBL:EJT99638.1, ECO:0000313|Proteomes:UP000030653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DJM-731 SS1 {ECO:0000313|EMBL:EJT99638.1,
RC ECO:0000313|Proteomes:UP000030653};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; JH795869; EJT99638.1; -; Genomic_DNA.
DR AlphaFoldDB; M5FU01; -.
DR STRING; 1858805.M5FU01; -.
DR HOGENOM; CLU_007383_9_2_1; -.
DR OMA; NEEWYFL; -.
DR OrthoDB; 987679at2759; -.
DR Proteomes; UP000030653; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF849; FATTY ACID HYDROXYLASE UHD1; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030653}.
FT DOMAIN 10..268
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 350 AA; 38280 MW; A523FE7AD9417AAE CRC64;
MVAVQPPALV LVTGASGFLA AHACQTLLEK EFKVRGTVRS KEKGEYLVNL YKNSNFSYTI
VPDIRPPNAF DEAVKGVDAV LHMASPFQVN VVDPEDLVRP AVQGTKGVLE SIQTFNCVTI
IPSVKRVIIT SSIASITVPS EPGHVFTETD WNTLSADIVA REGINAPGME KYRLSKVSAE
RAAWEFVDGQ KPTWDLVTVC PLMIYRTIIH ECASVERLNT SIAQLRVAFT PEGAKRGEDA
GRQAGNWADV RDVAEIHTQA LLQQKAGGNR FIAGGGPFSW QMMYDSVQAF GHIDGLDVDQ
LPKGTPGSDR NTVYMVTSNE KAKRELGIKF HLMGECVRDT LLSLKALGFF
//
