ID M5GEL4_DACPD Unreviewed; 797 AA.
AC M5GEL4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 13-SEP-2023, entry version 41.
DE RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN ORFNames=DACRYDRAFT_78285 {ECO:0000313|EMBL:EJU03368.1};
OS Dacryopinax primogenitus (strain DJM 731) (Brown rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Dacryopinax.
OX NCBI_TaxID=1858805 {ECO:0000313|EMBL:EJU03368.1, ECO:0000313|Proteomes:UP000030653};
RN [1] {ECO:0000313|EMBL:EJU03368.1, ECO:0000313|Proteomes:UP000030653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DJM-731 SS1 {ECO:0000313|EMBL:EJU03368.1,
RC ECO:0000313|Proteomes:UP000030653};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676,
CC ECO:0000256|PIRNR:PIRNR001251}.
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DR EMBL; JH795860; EJU03368.1; -; Genomic_DNA.
DR AlphaFoldDB; M5GEL4; -.
DR STRING; 1858805.M5GEL4; -.
DR HOGENOM; CLU_003782_1_0_1; -.
DR OMA; FHRKFPY; -.
DR OrthoDB; 20951at2759; -.
DR UniPathway; UPA00591; UER00663.
DR Proteomes; UP000030653; Unassembled WGS sequence.
DR GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR CDD; cd01319; AMPD; 1.
DR Gene3D; 4.10.800.20; -; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR006650; A/AMP_deam_AS.
DR InterPro; IPR006329; AMPD.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01429; AMP_deaminase; 1.
DR PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR PANTHER; PTHR11359:SF0; AMP DEAMINASE; 1.
DR Pfam; PF19326; AMP_deaminase; 1.
DR PIRSF; PIRSF001251; AMP_deaminase_met; 2.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR PROSITE; PS00485; A_DEAMINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030653}.
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 797 AA; 92134 MW; 8EC99FABB05FEB00 CRC64;
MKSIESMKLA HGTHDPIAAT PHTTPRARAN TVRGNIPPGL ELTPASLEKP EPVQEAQQPI
LPTLHIGSYA SVDGMMKQAA PEADGADAED EADAFITPEL LALYESFSKC LDLRDKYMNY
SMQRLGDNPQ HYDGYFTPLP PDLCDVNGVR EDATLPSDYP LHFPADPSLE PLAQGPNLST
PWRLYPKPPS PHWHWYARAA PSGVSNGAPE EEEEFDFEKC GIPGEHEWMF EMDDKGVYQV
YGTDDRQKPL FRVPDIREYF MDLDALLVVM TDGPAKSFAF RRLRYLSSKW TMYTLLNEYQ
ETADMKRVPH RDFYNLRKVD THVHHSSSMN QKHLLRFIKS KMKRTPNDTV IFRDGRELTL
AQVFESLNLT AYDLSIDTLD MHAHQDTFHR FDKFNLKYNP LGESRLREIF LKTDNYIKGR
YLAELTKELM TDLEQSKYQN CEWRISIYGR SPDEWDKLAK WVINNKLYSH NVRWLIQVPR
LYDVYKASGL LSNFQQILEN LFKPLFEVTK DPRSHPELHV FLQRVVGIDS VDDESKTERR
IYRKFPYPKV WDTKQNPPYN YWLYYLYANM CALNQWRRLR GFNTFVLRPH CGEAGDPDHL
ASAFMLAHSI SHGILLRKVP VLQYLFYLKQ IGLAMSPLSN NALFLTYERN PFPEYFKTGL
NVSISTDDPL QFHFTKEPLL EEYSVAAHIY KFSQASLAEL ARNSVIQSGF EMQIKRHWLG
HQWFLPGALG NDINKTNVPN IRLRYRHDTL MEELQMLSQG KKTLVVSRGH DGPVQPLTPD
TVAAKAMSIP MNSTGKH
//
