ID M5VKE2_PRUPE Unreviewed; 327 AA.
AC M5VKE2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN ORFNames=PRUPE_8G183600 {ECO:0000313|EMBL:ONH92606.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH92606.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH92606.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; CM007658; ONH92606.1; -; Genomic_DNA.
DR RefSeq; XP_007200400.1; XM_007200338.1.
DR AlphaFoldDB; M5VKE2; -.
DR STRING; 3760.M5VKE2; -.
DR EnsemblPlants; ONH92606; ONH92606; PRUPE_8G183600.
DR GeneID; 18769005; -.
DR Gramene; ONH92606; ONH92606; PRUPE_8G183600.
DR KEGG; pper:18769005; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_9_0_1; -.
DR OMA; CEKMQLW; -.
DR OrthoDB; 447101at2759; -.
DR Proteomes; UP000006882; Chromosome g8.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR CDD; cd08958; FR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR PANTHER; PTHR10366:SF821; TETRAKETIDE ALPHA-PYRONE REDUCTASE 1; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 10..249
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 327 AA; 36389 MW; 9CA3767A19DD21B5 CRC64;
MDQKLESGKV CVTGASGFLA SWLIKRLLLS GYHVTGTVRD PGNQKKLAHL WRLEGARERL
RLVKADLMEE GSFDDAILGC HGVFHSASPV LKPSSDPKTE ILEPAVEGTL NVLRSCKKNP
SLRRVVLTSS SSAVRVRPDE DFDSNIPLDE SSWSSVKICE TLQIWYPLSK ILAEKAAWDF
CKENGIDLVT VLPSFVIGPC LPSDLCSTAS DVLGLLKGET EKFKWHGRMG YVHIDDVALC
HISVYEHESA HGRYLCSSTV LDNNELASLL SRQYPSLPIP KRFEQLGRPR YDLNTSKLKS
LGFKFKTIQE MFDDCIASLV EQGHLTL
//
