ID M5VVS2_PRUPE Unreviewed; 922 AA.
AC M5VVS2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=PRUPE_7G106900 {ECO:0000313|EMBL:ONH96088.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH96088.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH96088.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; CM007657; ONH96088.1; -; Genomic_DNA.
DR RefSeq; XP_007203997.1; XM_007203935.1.
DR AlphaFoldDB; M5VVS2; -.
DR STRING; 3760.M5VVS2; -.
DR EnsemblPlants; ONH96088; ONH96088; PRUPE_7G106900.
DR Gramene; ONH96088; ONH96088; PRUPE_7G106900.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_1_1; -.
DR OMA; IDEHAFI; -.
DR Proteomes; UP000006882; Chromosome g7.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966:SF412; GLUTAMATE RECEPTOR 3.6; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 2.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT DOMAIN 470..797
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
SQ SEQUENCE 922 AA; 102441 MW; 915C7EB0DA008689 CRC64;
MNIVWLLVLM VFYNGVASNG VSTNVSTRPE FVNVGAVFSF NSIVGKVAKV AIEAAIEDVN
SDPAVLGGTK MIVQMQDSNY SGFLGIVEAL RFMEKDTVAI IGPQNAVTAH IISHIANELQ
VPLLSFSVTD PTLSSLQFPF FVRTTQNDLH QMAAVAAMID HYGWKEVIAL YVDDDYGRNG
IAALGDMLAE RRCKISYKAP LVLDPNQSNI TDLLVKVALT ESRIIVLHAY AGWGPQVFTV
AKYLGMMGTG YVWIATHWLT TQIDTNSPLP SSMMDDMQGV LTLRMYTPET ELKRKFVSRW
SNLTSGQTSK GKLGLNAYGL YAYDTVWLLA HAINAFFDQG GNISFSNDSR LTQLRRGDLN
LDAMSIFNGG NLLLRNILQV NMTGITGPVK FTPDRNLIHP AFEIINVIGT GIRKIGYWSN
YSGLSVVPPE YTKPPNRSSS NESLYGVIWP GQTTQKPRGW VFPNNGRHLK IGVPKRVSFR
EFVSYAEGND MFTGYCIDVF TAALNMLPYA VPYKLIPFGD GVKNPTSTEL VHKIQTGPFI
ESGLVVVAPV RTTLNSNPWA FLRPFNPTMW GVTAAFFLIV GTVVWILEHR LNDDFRGPPK
KQIVTILWFS FSTWFFAHRE NTVSTLGRLV LIIWLFVVLI INSSYTASLT SILTVQQLSS
SIKGLDTLLA SNDPIGYQQG SFARGYLTGE LNVDESGLVP LIMPDDYAKA LKDGPQRGGV
AAVIDEHAFI ELFLSSRCDF SIVGQEFTKT AWGIFVMFIS NQAFARDSPL SVDMSTAILK
LSENGDMQRI HDKWLISSSC ASQGAKLQVD RLQLKSFWGL FVLCGSACFL ALIIYFINML
HQFSKHYTEE VISAGSSTSA RLQTFISFVD EKEEEVKSRS KRRQMERMSN RSASEDESMY
NSKRRHIDQS SSRMSLDNGN NA
//
