ID M5VXI8_PRUPE Unreviewed; 642 AA.
AC M5VXI8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Xaa-Pro aminopeptidase P {ECO:0008006|Google:ProtNLM};
GN ORFNames=PRUPE_7G149300 {ECO:0000313|EMBL:ONH96748.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH96748.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH96748.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766, ECO:0000256|RuleBase:RU000590}.
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DR EMBL; CM007657; ONH96748.1; -; Genomic_DNA.
DR RefSeq; XP_007204612.1; XM_007204550.1.
DR AlphaFoldDB; M5VXI8; -.
DR STRING; 3760.M5VXI8; -.
DR EnsemblPlants; ONH96748; ONH96748; PRUPE_7G149300.
DR GeneID; 18770231; -.
DR Gramene; ONH96748; ONH96748; PRUPE_7G149300.
DR KEGG; pper:18770231; -.
DR eggNOG; KOG2413; Eukaryota.
DR HOGENOM; CLU_011781_2_2_1; -.
DR OMA; AMAKFPP; -.
DR OrthoDB; 869at2759; -.
DR Proteomes; UP000006882; Chromosome g7.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 6..138
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 332..568
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 581..640
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 642 AA; 71578 MW; 1D823C9D17D2526E CRC64;
MADTLSALRS LMASHSPPLD ALVVPSEDYH QSEYVSARDK RREFVSGFTG SAGLALVTKN
EARLWTDGRY FLQATQELSD QWQLMRMGED PAVDIWMADN LPRDSAIGID PWCVSIDTAQ
KWELAFSKKH QKLVQTSTNL VDEVWKNQPP AEINPVIVHP LQYAGRSVAD KLKDLRERLI
QENARGIIIS ALDEVAWLYN IRGSDVSYSP VVHAFAIVTS NSAFFYVDKR KVSSEVNTYL
EENGIEVRDY KSVSSDVALL ASNQLKPSFK ETEITGNGTN KAEDKNDDQI WADPGSCCYA
LYSKLNPEKV ILQQSPLALA KALKNPIELE GLKKAHIRDG AAVVQYLVWL DKQAQEIYGA
SGFFSEGEGM DKKKHSKTTK LTEVTASDKL EGFRASKENF RGLSFPTISS VGPNAAIIHY
SPQAETCAEF DPDSIYLFDS GAQYLDGTTD ITRTVHFGKP SAHEKACYTA VLKGHIALGN
ARFPNGTNGH ALDILARVPL WKSGLDYRHG TGHGIGSYLN VHEGPHLISF RPHARNVPLQ
ASMTVTDEPG YYEDGNFGIR LENVLIINQA DTKFNFGDKG YLQFEHITWA PYQRKLIDLS
LLAPEELEWL NTYHSKCRDI LAPYVDESEK AWLKKATEPI SA
//
