ID M5WE41_PRUPE Unreviewed; 861 AA.
AC M5WE41;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Extra-large guanine nucleotide-binding protein 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PRUPE_5G026100 {ECO:0000313|EMBL:ONI05840.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI05840.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI05840.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
RN [2] {ECO:0000313|EMBL:ONI05840.1}
RP NUCLEOTIDE SEQUENCE.
RA Verde I., Jenkins J., Dondini L., Micali S., Pagliarani G., Vendramin E.,
RA Paris R., Aramini V., Gazza L., Rossini L., Bassi D., Troggio M., Shu S.,
RA Grimwood J.H., Tartarini S., Dettori M.T., Schmutz J.;
RT "WGS assembly of Prunus persica.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; CM007655; ONI05837.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05838.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05839.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05840.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05841.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05842.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05843.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05844.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05845.1; -; Genomic_DNA.
DR EMBL; CM007655; ONI05846.1; -; Genomic_DNA.
DR RefSeq; XP_007210372.1; XM_007210310.1.
DR AlphaFoldDB; M5WE41; -.
DR STRING; 3760.M5WE41; -.
DR EnsemblPlants; ONI05837; ONI05837; PRUPE_5G026100.
DR EnsemblPlants; ONI05838; ONI05838; PRUPE_5G026100.
DR EnsemblPlants; ONI05839; ONI05839; PRUPE_5G026100.
DR EnsemblPlants; ONI05840; ONI05840; PRUPE_5G026100.
DR EnsemblPlants; ONI05841; ONI05841; PRUPE_5G026100.
DR EnsemblPlants; ONI05842; ONI05842; PRUPE_5G026100.
DR EnsemblPlants; ONI05843; ONI05843; PRUPE_5G026100.
DR EnsemblPlants; ONI05844; ONI05844; PRUPE_5G026100.
DR EnsemblPlants; ONI05845; ONI05845; PRUPE_5G026100.
DR EnsemblPlants; ONI05846; ONI05846; PRUPE_5G026100.
DR GeneID; 18776572; -.
DR Gramene; ONI05837; ONI05837; PRUPE_5G026100.
DR Gramene; ONI05838; ONI05838; PRUPE_5G026100.
DR Gramene; ONI05839; ONI05839; PRUPE_5G026100.
DR Gramene; ONI05840; ONI05840; PRUPE_5G026100.
DR Gramene; ONI05841; ONI05841; PRUPE_5G026100.
DR Gramene; ONI05842; ONI05842; PRUPE_5G026100.
DR Gramene; ONI05843; ONI05843; PRUPE_5G026100.
DR Gramene; ONI05844; ONI05844; PRUPE_5G026100.
DR Gramene; ONI05845; ONI05845; PRUPE_5G026100.
DR Gramene; ONI05846; ONI05846; PRUPE_5G026100.
DR KEGG; pper:18776572; -.
DR eggNOG; KOG0082; Eukaryota.
DR HOGENOM; CLU_006703_0_0_1; -.
DR OMA; DYDQVGP; -.
DR OrthoDB; 1221906at2759; -.
DR Proteomes; UP000006882; Chromosome g5.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR36486; OS01G0977800 PROTEIN; 1.
DR PANTHER; PTHR36486:SF4; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 61..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 861 AA; 97700 MW; 881D4B95FA801A72 CRC64;
MEQKEGESWR ELVRKMLPPG ASIPEDASDL DYSIAMEYVG PPVSYDVPRV EPLDVSSRAI
PTAEPLSESQ RSVTNMGPPV IEPIPLPVSR IAGVTSSPTQ SPRVSGSSES VVSVLQNPDF
SSASPSASPG SVHNPPGIHP KQVSNEVKRA PVVTFNTVDR SQRKEVDVEQ PVFTAYVGVS
KEKKKKKSRV CYRCRKAKWE TKESCLVCDA KYCSNCVLRA MGSMPEGRKC VTCIGEPIDE
SKRLKLGKQS RLLSRLLSPL EVKQIMKAEK ECSANQLRPE QLIVNGFPLK PEEMAELLGC
PLPPRKLKPG RYWYDKESGL WGKEGEKPDR IISSNLNFTG KLSPDASNGN TEVYINGREI
TKLELRVLRV ANVQCPRDTH FWVYDDGRYE EEGQNNIRGN IWEKATTRFV CSLFSLPVPH
GQPQGPRDEA SNYTTVPNYL EQKKIQKLLL LGLHGSGTST IFKQAKFLYG NKFTAEELQD
IKLMIQSNMY KYLSILLDGR ERFEEEALSR MEGHGSHDQN TKAGGEIDLD ETTQCVYSIN
PRLKHFSDWL LDIIATGDLD AFFPAATREY APLVEEVWKD PAIQETYKRR DELHFLPDVA
EYFLSQAVEV SGNEYEPSER DILYAEGVTQ GNGLAFIEFS LDDRSPMSET YTENLEAPPP
PLTKYQLIRV NAKGMNEGCK WVEMFEDVRV VVFCVALSDY DQMWVAPDNS GSGTLLQNKM
IQSKELFETM VRHPCFKDTP FVLILNKYDL FEDKVNQAPL STCEWFNDFS PVKPHHNNQS
LAHQAYFYVA MKFKDLYASI TSRKLFVWQA RARERVTIDE AFKYIREVLK WDEEKEETYY
GGPEDSFYST DMSSSPYVRQ E
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