ID M5WQV7_PRUPE Unreviewed; 761 AA.
AC M5WQV7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=PRUPE_3G026700 {ECO:0000313|EMBL:ONI15114.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI15114.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI15114.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; CM007653; ONI15114.1; -; Genomic_DNA.
DR RefSeq; XP_007214978.1; XM_007214916.1.
DR AlphaFoldDB; M5WQV7; -.
DR STRING; 3760.M5WQV7; -.
DR EnsemblPlants; ONI15114; ONI15114; PRUPE_3G026700.
DR GeneID; 18784434; -.
DR Gramene; ONI15114; ONI15114; PRUPE_3G026700.
DR KEGG; pper:18784434; -.
DR eggNOG; KOG0497; Eukaryota.
DR HOGENOM; CLU_009074_2_0_1; -.
DR OMA; EFMANTM; -.
DR OrthoDB; 608at2759; -.
DR Proteomes; UP000006882; Chromosome g3.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IBA:GO_Central.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IBA:GO_Central.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF58; BETA-AMYRIN SYNTHASE-RELATED; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 99..402
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 418..753
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 761 AA; 87338 MW; 3C7A9951F8C04C01 CRC64;
MWKLKVADGG NDPYIYSTNN FVGRQIFEFD PEAGTPEERA EVEEARLNFY NNRHQVKPSG
DLLWRMQFLK ENNFKQTIPP VKVEDGEEIT YEKATASLRR SVHFFSALQA SDGHWPAENA
GPLFFLPPLV MCTYITGHLN TVFPAEHRKE ILRYIYYHQN QDGGWGLHIE GHSTMFCTAL
SYICMRILGE GPDGGQDNAC ARVRKWILDH GSVTHMPSWG KTWLSILGVF EWSGSNPMPP
EFWVLPSFLP MHPAKMWCYC RMVYMPMSYL YGKRFVGPIT PLILQLREEL YAQPYNEINW
KGVRHHCAKE DIYYPHPWIQ DIMWDSLYIC TEPLLTRWPF NKLVREKALQ VTMKHIHYED
ENSRYITIGC VEKVLCMLAC WAEDPNGDYF KKHLARIPDY LWVAEDGMKM QSFGSQEWDT
GFAIQALLAS NLTDEIGPTL ARGHDFIKKS QVKDNPSGDF KSMYRHISKG SWTFSDQDHG
WQVSDCTAEG LKCCLLFSMM RPDIVGEKME PERLYDSINV LLSLQSKNGG LAAWEPAGAA
DWLEMLNPTE FFADIVVEHE YVECTSSAIQ ALVLFKKLYP GHRKKEIDHF ITNATQYLES
IQMPDGSWYG NWGVCFTYGS WFALGGLAAA GKTFINCLAM RKGVNFLLKT QRENGGWGES
YLSCPKKEYV PLEGNRSNLV HTGWAMMGLI HAGQADRDPA PLHRAAKLII NSQMENGDFP
QQEITGVFMK NCMLHYAAYR NIYPLWALAE YRKWVSLPSQ A
//
