ID M5X2E6_PRUPE Unreviewed; 1266 AA.
AC M5X2E6;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PRUPE_2G098100 {ECO:0000313|EMBL:ONI21907.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI21907.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI21907.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; CM007652; ONI21907.1; -; Genomic_DNA.
DR RefSeq; XP_007218890.1; XM_007218828.1.
DR AlphaFoldDB; M5X2E6; -.
DR STRING; 3760.M5X2E6; -.
DR EnsemblPlants; ONI21907; ONI21907; PRUPE_2G098100.
DR GeneID; 18787387; -.
DR Gramene; ONI21907; ONI21907; PRUPE_2G098100.
DR KEGG; pper:18787387; -.
DR eggNOG; KOG1939; Eukaryota.
DR HOGENOM; CLU_002157_0_1_1; -.
DR OMA; TDCNVML; -.
DR OrthoDB; 674at2759; -.
DR Proteomes; UP000006882; Chromosome g2.
DR GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IBA:GO_Central.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 10..214
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 235..534
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 558..711
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 738..1265
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1266 AA; 137961 MW; 609215B60D02A7CB CRC64;
MGSANDNKLR FCIDRGGTFT DVYAEIPGQP DGQVLKLLSV DPSNYDDAPV EGIRRILEEF
TGKKISRASK IPTDKIEWIR MGTTVATNAL LERKGERIAL CVTRGFRDLL QIGNQARPKI
FDLTVSKPSN LYEEVIEVDE RVELANDNQD SSSASLVKGV SGEMVKVVKP IDVETLKPLL
QGLLEKGISC LAVVLMHSYT YPQHEVAVER LAESLGFRHV SLSSALTPMV RAVPRGLTAS
VDAYLTPVIK EYLSGFMSKF DEGVEKVNVL FMQSDGGLAP ESRFSGHKAV LSGPAGGVVG
YSQTLFGLET EKPLIGFDMG GTSTDVSRYA GTYEQVLETQ IAGAIIQAPQ LDISTVAAGG
GSKLKFQFGA FRVGPESVGA HPGPVCYRKG GELAVTDANL VLGYVIPDYF PSIFGPNEDE
PLDIRATRDE FDKLASQINS YRKSQDPSAK DMTVEEIALG FVNVANETMC RPIRQLTEMK
GHETRNHALA CFGGAGPQHA CAIARSLGMK EVLIHRFCGI LSAYGMGLAD VVEEAQEPYS
AVYSLESVQE ASHREAILLS QVRQKLQEQG FRDENMTTET YLNLRYEGTD TSIMVKKRIT
EDGRGCNYNL DFVELFQQEY GFKLLNRNIL ICDVRVRGVG VTNILKPLAL ERTSCSPKVE
GNYKVYFGNG WQETPLYKLE KLGYGHIMAG PAIIMNGNST VIVEPNCKAI ITKYGNIKIE
IDSTSSTMKV VEKVANVVQL SIFNHRFMGI AEQMGRTLQR TSISTNIKER LDFSCALFGP
DGGLVANAPH VPVHLGAMSS TVRWQINYWG DNLSEGDVLV TNHPCAGGSH LPDITVITPV
FDNGKLVFFV ASRGHHAEIG GITPGSMPPF SKSIWEEGAA LKAFKLVEKG IFQEEGITKL
LRFPCSDELA QKIPGTRRLQ DNLSDLRAQV AANKRGITLI KELIEQYGLD TVQAYMTYVQ
LNAEEAVREM LKSVAARVLS QPSSSGDRSS VTIEEEDYMD DGSIIHLKLT IDSDNGEANF
DFSGTSPEVY GNWNAPEAVT AAAVIYCLRC LVDVDIPLNQ GCLAPVKIYI PPGSFLSPSD
KAAVVGGNVL TSQRITDVVL TAFQACACSQ GCMNNLTFGD ETFGYYETIG GGSGAGPTWD
GTSGVQCHMT NTRMTDPEIF EQRYPVLLHK FGLRENSGGV GYHKGGDGLV REIEFKRPIV
VSILSERRVH TPRGLKGGKD GARGANFLIT QDKRRVYLGG KNTVEVQPGE ILQILTPGGG
GWGSPL
//
