ID M5X3L2_PRUPE Unreviewed; 1473 AA.
AC M5X3L2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=PRUPE_2G239100 {ECO:0000313|EMBL:ONI24408.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI24408.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI24408.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
RN [2] {ECO:0000313|EMBL:ONI24408.1}
RP NUCLEOTIDE SEQUENCE.
RA Verde I., Jenkins J., Dondini L., Micali S., Pagliarani G., Vendramin E.,
RA Paris R., Aramini V., Gazza L., Rossini L., Bassi D., Troggio M., Shu S.,
RA Grimwood J.H., Tartarini S., Dettori M.T., Schmutz J.;
RT "WGS assembly of Prunus persica.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; CM007652; ONI24408.1; -; Genomic_DNA.
DR EMBL; CM007652; ONI24409.1; -; Genomic_DNA.
DR RefSeq; XP_007218887.1; XM_007218825.1.
DR STRING; 3760.M5X3L2; -.
DR EnsemblPlants; ONI24408; ONI24408; PRUPE_2G239100.
DR EnsemblPlants; ONI24409; ONI24409; PRUPE_2G239100.
DR GeneID; 18784935; -.
DR Gramene; ONI24408; ONI24408; PRUPE_2G239100.
DR Gramene; ONI24409; ONI24409; PRUPE_2G239100.
DR KEGG; pper:18784935; -.
DR eggNOG; KOG0928; Eukaryota.
DR HOGENOM; CLU_001204_1_0_1; -.
DR OMA; CRDIRHH; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000006882; Chromosome g2.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 558..747
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 283..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1444..1473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..954
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1473 AA; 164521 MW; 8F94A1D9D775E82A CRC64;
MGRLKLQNGI KAIDEEPGNC DATYSKKDTL ACIINSEIGA VLAVMRRNVR WGGRYISGDD
QLEHPLIQSL KVLRKQIFSW QHQLHTINPA AYLQPFLDVI RSDETGAPIT GVALSSVYNI
LTLDVIDQNS VNVEDAMHLL VDAITGCRFE VTDPASEEVV LMKILQVLLA CMKSKASVIL
SNQHVCTIVN TCFRIVHQAG TKGELLQRIA RHTMHELVRC IFSHLPDVQN TERALSNGNN
TINREIAGIN NEYPSGSRQL ENGNVSSEFD SQLLSTNPAL NASSGLVESG MDEKTTGASS
GKETVQYDSR LMAEPFGVPC MVEIFNFLCS LLNVVEHIGM GPRSNTISFD EDVPLFALGL
VNSAIELGGS SIQNHPKLLS LVQDELFQNL MQFGLSMSPL ILSMVCSIVL NLYHHLRTEL
KLQLEAFFSC VILRLAQSRY GASYQQQEVA MEAVVDFCRQ KTFMVEMYAN LDCDITCSNA
FEDLANLLSK SAFPVNFPLS SIHILALDGL IAIIQGMAER SGNGSVSSAE TLTNLEEYTP
FWLMKCDDYS DPNHWVPFVR RRKYIKRRLM IGADHFNHDP KKGLEFLQGT HLLPDKLDPE
SVACFFRYTS GLDKNLVGDF LGNHDEFCIQ VLHEFAGTFD FQDMNLDTAL RLFLETFRLP
GESQKIQRVL EAFSERYYEQ SPQILANKDA ALLLSYSIIM LNTDRHNVQV KKKMTEEDFI
RNNRHINGGD DLPREFLSEL YHSICKNEIR TTPEQGASFP EMTPSRWIDL IHKSKKNAPF
IVSNFRPHLD QDMFAIMSGP TIAAISVVFD HAEHEEIYQT CIDGFLSVAK IAACYHLEDV
LDDLVVSLCK FTTLLNPSVD EPVLAFGDDP KARMSTVTVF TIANTYGDYI RTGWRNILDC
ILRLHKLGLL SACVASEAAG DSEVSADTGH GNPITNSLSS VHMPSVSTPR RSSGLMGRFS
QLLSLDTEEP RSQPTEEELA AHQRTLQTVQ KCHIDGIFSD SKFLQAESLL QLAQALIWAG
GRPHKGSSSP EDEDTGVFCL ELLIAITLNN RDRIMLLWQI VYEHISNIVQ STVMPCALVE
KAVFGLLRIC QRLLPYKENL ADELLRSLQL VLKLDARVAD AYCEQITQEV GRLVKANASH
IRSQLGWRII TSLLSITARH PEASEAGFDA LFFIMSDGTH LLPANYVLCV DASRQFAESR
VGEVDRSVCA LDLMAGSVDC LARWVCEAKQ SMNDEEAVKM SQDIGKMSQD IGEMWLRLVQ
GLRKVCLDQR EEVRNHALSL LRKCLTGVDG IPLPPGLWLQ CFDMVIFTML DDLLEIAQRH
SPKDYRNMEG TLILALKLLS KVFLQLLPDL SQLTTFCKLW LGVLSRMEKY MKVKIGGKKS
DKLRDQVPEL LKNTLLVMIL RGVLVERSDL GDDSLWELTW RLVNNIAPSL QSEIFRDPIL
EQSETKQGET GGVSEATGTL LPTDTTSAEG SGS
//
