ID M5X9N4_PRUPE Unreviewed; 733 AA.
AC M5X9N4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=PRUPE_3G269000 {ECO:0000313|EMBL:ONI19276.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI19276.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI19276.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CM007653; ONI19276.1; -; Genomic_DNA.
DR RefSeq; XP_007217024.1; XM_007216962.1.
DR AlphaFoldDB; M5X9N4; -.
DR STRING; 3760.M5X9N4; -.
DR EnsemblPlants; ONI19276; ONI19276; PRUPE_3G269000.
DR GeneID; 18781573; -.
DR Gramene; ONI19276; ONI19276; PRUPE_3G269000.
DR KEGG; pper:18781573; -.
DR eggNOG; KOG2166; Eukaryota.
DR HOGENOM; CLU_004747_7_1_1; -.
DR OMA; KQLIMDP; -.
DR OrthoDB; 21270at2759; -.
DR Proteomes; UP000006882; Chromosome g3.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 374..602
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 733 AA; 85563 MW; B74798A227697CEF CRC64;
MSAQKKRNFQ IEAFKHRVVV DPKYAEKTWK ILEHAIHEIY NHNASGLSFE ELYRNAYNMV
LHKFGEKLYS GLVTTMTYHL KEISKSIEAA QGELFLEELN RKWAEHNKAL QMIRDILMYM
DRTFIPSTHK TPVHELGLNL WRDVVIHSSK TQARLLDTLL ELVHRERSGE VINRGLMRNI
IKMLMDLGSS VYQDDFEKHF LEVSADFYRC ESQEFIESCD CGNYLKKAER RLMEEMERVS
HYLDARSEAK ITNVVEKEMI ESHMNRLVHM ESSGLVNMLV DDKYDDLGRM YSLFRRVQNG
LVIVRDVMTA YIRDTGKQLV TDPERLRDPV DFVQRLLDLK DKYDKVINLA FNNDKTFQNA
LNSSFEYFIN LNARSPEFIS LFVDDKLRKG LRGVSEEDVE VVLDKVMMLF RYLQEKDVFE
KYYKQHLAKR LLSGKTVSDD AERSLIVKLK TECGYQFTSK LEGMFTDMKT SQDTMHGFYS
AVGHQLGDSP TLAVQVLTTG SWPTQPSATC NLPAEILWVC EKFKSYYLGT HTGRRLSWQT
NMGTADLKTT FGKGQKHELN VSTYQMCVLM LFNNTDRLTY KEIEQATEIP ASDLKRCLQS
LACVKGKNVL RKEPMSKDIA EDDAFFFNDK FTSKFFKVKI GTVVAQRESE PENQETRQRV
EEDRKPQIEA AIVRIMKSRR VLDHNNIVAE VTKQLQARFL PNPVVIKKRI ESLIEREFLE
RDKTDRKLYR YLA
//
