ID M5XRN7_PRUPE Unreviewed; 843 AA.
AC M5XRN7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Beta-adaptin-like protein {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=PRUPE_1G453100 {ECO:0000313|EMBL:ONI33920.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI33920.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI33920.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- FUNCTION: Subunit of clathrin-associated adaptor protein complex that
CC plays a role in protein sorting in the late-Golgi/trans-Golgi network
CC (TGN) and/or endosomes. The AP complexes mediate both the recruitment
CC of clathrin to membranes and the recognition of sorting signals within
CC the cytosolic tails of transmembrane cargo molecules.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SUBUNIT: Adaptor protein complexes are heterotetramers composed of two
CC large adaptins (beta-type subunit and alpha-type or delta-type or
CC epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit)
CC and a small adaptin (sigma-type subunit).
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
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DR EMBL; CM007651; ONI33920.1; -; Genomic_DNA.
DR RefSeq; XP_007227007.1; XM_007226945.1.
DR AlphaFoldDB; M5XRN7; -.
DR STRING; 3760.M5XRN7; -.
DR EnsemblPlants; ONI33920; ONI33920; PRUPE_1G453100.
DR GeneID; 18790396; -.
DR Gramene; ONI33920; ONI33920; PRUPE_1G453100.
DR KEGG; pper:18790396; -.
DR eggNOG; KOG1061; Eukaryota.
DR HOGENOM; CLU_006320_4_5_1; -.
DR OMA; ANCMHAL; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000006882; Chromosome g1.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF4; AP-4 COMPLEX SUBUNIT BETA-1; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 721..838
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
SQ SEQUENCE 843 AA; 93372 MW; D8B58EC6F28B6013 CRC64;
MAPPPQSQRS SSPSQPSGKG EVADVKSQLR NLAGSRAPGV DDSKRELFKK VISYMTIGID
VSSVFGEMVM CSATSDIVLK KMCYLYVGNY AKVNPDLALL TINFLQRDCK DADPMIRGLA
LRSLCSLRVA NLVEYLVGPL GAGLKDNNSY VRMIAVMGVL KLYHISASTC VDADFPAMLK
HLLLNDRDTQ VVANCLSALQ EIWSLEGSTS EEVSREREIL LSKPVIYYLL NRIREFSEWA
QCLVLELVGK YVPADSSEIF DVMNLLEDRL QHANGAVVLA TTKVFLQLTL SMTDVHQQVY
ERIKAPLLTL VSSGSPEQSY AVLSHLHLLV TRAPFIFSSD YKHFYCQYNE PSYVKKLKLE
MLTAVANESN TYEIVTELCE YAANVDIPIA RESIRAVGKI ALQQYDVNAI VDRLLQFLEM
EKDYVTAEAL VLVKDLLRKY PQWSHDCIAV VGNISSKNVQ EPKAKAALIW MLGEYSQEMQ
DAPYILESLI ENWEDEHSAE VRLHLLTAVM KCFFKRPPET QKSLGAALAA GLADFHQDVH
DRALFYYRLL QYDMSTAEQV VNPPKQAVSV FADTQSSEIK DRIFDEFNSL SVVYQQPSYM
FTYKEHRGPF EFSDEIGNLS IGTESADTVA QAHRVEANDK DLLLSTSEKE ETRGLNNNSS
AYSAPSYDVS SVPVPTSQMS ELAISNPSVP GNAPQSGFAI DDLLGLGLPA APAPAPSPPP
LKLNPKAVLD PTTFQQKWRQ LPISLSQEYS ITPEGVAALT TPQALLRHMQ GQAIHCIASG
GQSPNFKFFF FAQKAEESST FLVECIVNTS SAKAQIKIKA DDQSATQPFS SVFQSALSKF
GMP
//
