ID   M6KKM0_LEPIR            Unreviewed;       409 AA.
AC   M6KKM0;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Bacterial capsule synthesis protein {ECO:0000313|EMBL:EMN28327.1};
GN   ORFNames=LEP1GSC083_1427 {ECO:0000313|EMBL:EMN28327.1};
OS   Leptospira interrogans serovar Pyrogenes str. L0374.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1049928 {ECO:0000313|EMBL:EMN28327.1, ECO:0000313|Proteomes:UP000012137};
RN   [1] {ECO:0000313|EMBL:EMN28327.1, ECO:0000313|Proteomes:UP000012137}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L0374 {ECO:0000313|EMBL:EMN28327.1,
RC   ECO:0000313|Proteomes:UP000012137};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Peacock S.J., Thaipadungpanit J.,
RA   Wuthiekanun V.W., Day N.P., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA   Fouts D.E.;
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CapA family.
CC       {ECO:0000256|ARBA:ARBA00005662}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMN28327.1}.
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DR   EMBL; AHMZ02000137; EMN28327.1; -; Genomic_DNA.
DR   AlphaFoldDB; M6KKM0; -.
DR   Proteomes; UP000012137; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07381; MPP_CapA; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR019079; Capsule_synth_CapA.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   PANTHER; PTHR33393:SF11; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   Pfam; PF09587; PGA_cap; 1.
DR   SMART; SM00854; PGA_cap; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          76..319
FT                   /note="Capsule synthesis protein CapA"
FT                   /evidence="ECO:0000259|SMART:SM00854"
SQ   SEQUENCE   409 AA;  45899 MW;  812AC93FB40C668D CRC64;
     MLFLFPILRR FRILILKLFG FCFFCGLGLL SCLPGFLKES STENSQVNSS STFETLQDKI
     DSVLHPDHNQ DPGLLKLLAG GDVMFNWGIR DTIRKHGEIA PVEGLRPLFN EADFRMINLE
     TPIVASKTEE SKKAYIFTAH EKDLNSLKYL GVDMVFLGNN HSFDHGQQGM NETLDILNKN
     NILFVGAGKK LPEVLEPLNL NLKGSDLRIH SVTAIAEQTH YATATRSGVA PFLFPSLRAT
     FFEKNILPKN HSTPVRIVSL HWGVEYSPFP TSDQRKIARS LIDSGVKIVI GHHPHIPQGV
     EVYKGGVILY SLGNLIFGSR NSYLNHNLIA ILHIRNNHLE RVELVPIFGK FQKEDHKIRP
     VKGVEAQEFL HEIAVLSAEL GTKLRVEGDR AFLDLPTNST LTPVSKRKK
//