ID M6VGJ1_9LEPT Unreviewed; 637 AA.
AC M6VGJ1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Succinate dehydrogenase or fumarate reductase, flavoprotein subunit {ECO:0000313|EMBL:EMO56602.1};
DE EC=1.3.99.1 {ECO:0000313|EMBL:EMO56602.1};
GN Name=sdhA {ECO:0000313|EMBL:EMO56602.1};
GN ORFNames=LEP1GSC161_2827 {ECO:0000313|EMBL:EMO56602.1};
OS Leptospira santarosai str. CBC1416.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1193059 {ECO:0000313|EMBL:EMO56602.1, ECO:0000313|Proteomes:UP000012149};
RN [1] {ECO:0000313|EMBL:EMO56602.1, ECO:0000313|Proteomes:UP000012149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBC1416 {ECO:0000313|EMBL:EMO56602.1,
RC ECO:0000313|Proteomes:UP000012149};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Matthias M.A., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMO56602.1}.
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DR EMBL; AKWE02000164; EMO56602.1; -; Genomic_DNA.
DR AlphaFoldDB; M6VGJ1; -.
DR Proteomes; UP000012149; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EMO56602.1}.
FT DOMAIN 36..441
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 503..636
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 330
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 637 AA; 70643 MW; 80EADAE76DE60C1B CRC64;
MSLDSKIPNG PIEKKWSNHK ANIKLVNPAN KRKFNIIVVG SGLAGASASA TLAELGYNVK
TFCFQDSPRR AHSIAAQGGI NAAKNYQNDG DSVYRLFYDT VKGGDFRARE ANVHRLAEVS
VNIIDQCVAQ GVPFAREYGG HLSNRSFGGA QVSRTFYAKG QTGQQLLLGA YSALSRQIGL
GAVKMYPRTE MVELIVIDGH AKGIVVRDLV TGKLSTHMAD AVVLGTGGYG NVFFLSTNAK
GCNVTATWKA HKKGAFFANP CYTQIHPTCI PVSGDHQSKL TLMSESLRND GRIWVPKNKG
DKRFPADIPE TERDYYLERK YPSYGNLSPR DIASRAAKEA CDAGLGVGES GQGVYLDFAD
SIKRLGEDKI RDRYENLFQM YEQITGENPY KQPMRIYPAV HYTMGGLWVD YNLMSNLPGL
FVIGEANFSD HGANRLGASA LMQGLADGYF ILPYTIGNYL AGVGFNSHPK EDHPEAKKAL
FEAEETTKKF LSINGKRTVD SFHRQLGKLM WDKCGMARND KGLKEALSEI PKIREEFWKN
VNVPGSGTEL NQSLEKAGRV ADFLEFAELL CLDALTREES CGGHFREEHQ EEGEAKRNDD
KFCHATAWEF NGVDKKPTEH REKLEFENVH LATRSYK
//
