ID M6VHY4_9LEPT Unreviewed; 306 AA.
AC M6VHY4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Trk system potassium uptake protein TrkA, N-terminal domain protein {ECO:0000313|EMBL:EMO56455.1};
GN ORFNames=LEP1GSC161_1804 {ECO:0000313|EMBL:EMO56455.1};
OS Leptospira santarosai str. CBC1416.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1193059 {ECO:0000313|EMBL:EMO56455.1, ECO:0000313|Proteomes:UP000012149};
RN [1] {ECO:0000313|EMBL:EMO56455.1, ECO:0000313|Proteomes:UP000012149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBC1416 {ECO:0000313|EMBL:EMO56455.1,
RC ECO:0000313|Proteomes:UP000012149};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Matthias M.A., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMO56455.1}.
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DR EMBL; AKWE02000173; EMO56455.1; -; Genomic_DNA.
DR AlphaFoldDB; M6VHY4; -.
DR Proteomes; UP000012149; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..260
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 306 AA; 34282 MW; 35DCFA04231F2E93 CRC64;
MKIPIPSIQI ISVSLIAVVF VIFSRVITVA TPVYFSGRGL RAGIVTGLNL AQISEFSLVI
LSLGMGYGHI SKELESTVLT SMILASVVST YIIFFNDPIS RFVLRLLGTI GLKEEDRVEF
HTDGRPKRDI VILGYFRIAQ SLLEEMEREK PEWLNRILIV DFNPVFRRSL EAKGIRWAYG
DLANPETLHH LGIEDARYVI CTISDMILKG TTNRRLLESI KGICRHTQPS IILTTDDPQE
AETLIENGAA HVVVPGKISG MSLFKEMKTI VDHSKSGIEN VPVETKKKRS NKQLVSKSKV
RVKRIN
//
