ID M7AFQ1_CHEMY Unreviewed; 805 AA.
AC M7AFQ1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Dynein regulatory complex protein 1 {ECO:0000256|ARBA:ARBA00013815};
DE AltName: Full=Coiled-coil domain-containing protein 164 {ECO:0000256|ARBA:ARBA00031554};
GN ORFNames=UY3_19251 {ECO:0000313|EMBL:EMP23691.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP23691.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the DRC1 family.
CC {ECO:0000256|ARBA:ARBA00009688}.
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DR EMBL; KB608655; EMP23691.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AFQ1; -.
DR STRING; 8469.M7AFQ1; -.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005858; C:axonemal dynein complex; IEA:InterPro.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR GO; GO:0070286; P:axonemal dynein complex assembly; IEA:InterPro.
DR InterPro; IPR039505; DRC1/2_N.
DR InterPro; IPR039750; DRC1/DRC2.
DR InterPro; IPR029440; DRC1_C.
DR PANTHER; PTHR21625:SF1; DYNEIN REGULATORY COMPLEX PROTEIN 1; 1.
DR PANTHER; PTHR21625; NYD-SP28 PROTEIN; 1.
DR Pfam; PF14772; NYD-SP28; 1.
DR Pfam; PF14775; NYD-SP28_assoc; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 167..268
FT /note="Dynein regulatory complex protein 1/2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14772"
FT DOMAIN 697..756
FT /note="Dynein regulatory complex protein 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14775"
FT REGION 42..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 349..454
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 65..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 805 AA; 92604 MW; 4C454467235683F4 CRC64;
MSFSRSGPSA TLRRHVLQSL RAFGSCPSVP LKTQSKWRTC HRSAAEDLEQ PGATEGPAAE
VLPKDCRAAG RDRFSGSRED PLNRRQSALQ LTPVLQLSEK SKGSRLESVS HRRSAVKTPG
EALGEDPDAK KAEAEDLSRS HKQIEESRQR LAKLLNDGTQ LVTNIQVAAD ARETQRRAEE
DELKRQRLEK LENESKTNQD KFEEITSKWG SAKEKTIPQD LWDVLNQQQQ QCALLIEEKN
KLISELQQEL KSKDDHYVKD LKKQSDDINL LVERMEEQIR NLMKTYRREL TQIEKAFELE
RRELLSSNKK KWEQAMQAHN AQELENLITR MQTVEEYEKQ LNQLQVKDAE EYATIKIQLE
NDVQILEQQL QQMKAIYQLN QEKLEYNFQV LKKRDEENTI IKSQQKRKLN RLHDVLNNLR
IKLAKQIKQF QEENQNLTAD YKRIVEQYKD LQRTMRHFAV VDAQKFLEIW LMNEEEAKGL
MWKALEADRV IHTQQLGLPW VEPDYWFLDN VGPIVHRKAI KSASKLAQEV MALTESSQQE
EEEEAAEEGR QEAAEAGEEV KPPRHVLVKS VKHILELLCD ESALEIDNED DVYTLVDFFL
KFKAQQVVSS QSKEWAVEEG PEDFAVDAAK DDGGSAAPKE EGTAHQSSAA SLSSLLFHHD
DVLKALKAFV RDFQKSRDKR PQVKKVMEER DNSKDSEYWE ALAHVIPESK LKVWDALEAA
LEKYYSVLSQ RSKLLTDLDG LQQQNTELHM LLHQYLTSKV SGSWYLAGPR ASGQLHSLAV
GALRECFLLR LPEALHGSCP LAPWQ
//
