ID   M7AI47_CHEMY            Unreviewed;      1213 AA.
AC   M7AI47;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=TBC1 domain family member 9B {ECO:0000313|EMBL:EMP24686.1};
DE   Flags: Fragment;
GN   ORFNames=UY3_18233 {ECO:0000313|EMBL:EMP24686.1};
OS   Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX   NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP24686.1, ECO:0000313|Proteomes:UP000031443};
RN   [1] {ECO:0000313|Proteomes:UP000031443}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
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DR   EMBL; KB598657; EMP24686.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7AI47; -.
DR   STRING; 8469.M7AI47; -.
DR   eggNOG; KOG4347; Eukaryota.
DR   Proteomes; UP000031443; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd13351; PH-GRAM1_TCB1D9_TCB1D9B; 1.
DR   CDD; cd13354; PH-GRAM2_TCB1D9_TCB1D9B; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   InterPro; IPR036014; TCB1D9/TCB1D9B_PH-GRAM1.
DR   InterPro; IPR036017; TCB1D9/TCB1D9B_PH-GRAM2.
DR   PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR47666:SF3; TBC1 DOMAIN FAMILY MEMBER 9B; 1.
DR   Pfam; PF02893; GRAM; 2.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00568; GRAM; 2.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT   DOMAIN          472..659
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   DOMAIN          850..878
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          936..956
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1031..1123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        939..956
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1031..1056
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EMP24686.1"
FT   NON_TER         1213
FT                   /evidence="ECO:0000313|EMBL:EMP24686.1"
SQ   SEQUENCE   1213 AA;  137690 MW;  A13DD581B3ED3F34 CRC64;
     GLLVGTLDVV LDSSARVAPY RILHQTQDSQ IYWAVACGSS RKEITKHWEW LENNLLQTLS
     IFDNEDDITT FIKGKIHGII AEENKNQQPL GEEDPGKFKE AELKMRKQFG MPEVEKLVNY
     YSCSYWKGRV PRQGWLYLTV NHLCFYSFLL GKEVTLIVQW VDVTQLEKNA TLLFPECIKV
     STRDSELYFS MFLNINETFK LMEQLANIAM RQLLDNEGFL EDKSLPKPSK PLKNISALKR
     DLDARAKNDW YRATFRLPKD ERLDGHTDCT LWTPFNKMHI PGQMFVSNNY ICFASKAEEA
     CHLIIPLREV AVVEKADSSS VLPRPLSIST KSKMTFLFAN LKDRDFLVQR ISDFLQRTPS
     KKSDGSGRKW KGSFSDTGCE VLEQEVSSSS PPAVSPTSTL NNQLVPSFCT GEVPTASQGL
     LKLFRRNSEE LLGPKGAKEK MKEESWNIHF FEYGRGMCMY RTAKTRELVL KGIPENLRGE
     LWLLFSGAWN EMVTLPGYYA ELVEKSMGKY SLATEEIERD LHRSMPEHPA FQNELGIAAL
     RRVLTAYAFR NPTIGYCQAM NIVTSVLLLY CNEEEAFWIL VALCERMLPD YYNSRVVGAL
     VDQGIFEELT RDYLPQLSEK MQELGVISTI SLSWFLTLFL SVMPFESAVV IVDCFFYEGI
     KLILQVSLAI LDANMEKLLN CCDEGEAMTV LGRYLDNVVN RQSISPPIPH LHALLTSGDE
     PPLEVDIFEL IKTSYEKFSN LRADDIEQMR FKQRLKVIQS LEDTAKRSVV RAISGDIGFS
     MEQLEELYVV FKAKHLTSCY WGSSRTAAAH RDQSLPYLEQ YRIDLEQFRE LFASLTLWSC
     GLHTPVLAGR MFRLLDENRD SLINFKEFVT GMSGMYHGDL TEKLKLLYKL HLPPALISEE
     AESALEATSY FTEDISTEGY SLSHFSNINV CLEAATQEDR GGRNGDSKEK EEKGTSPQDY
     RYYLRMWAKE KYSKKETIKD LPKMNQEQFI ELCKTLYNMF SEDPVEQELY HAIATVASLL
     LRIGEVGKKF SNRPMKKTDD CKANNTDAES EEESPTSEHS QNSAVEQQPQ ADPEDRASGD
     IQAGKTHQEK QIQGDGDGGE GSGSPIQLPS DDETKDDMSM SSYSMVSTGS LQCEDIADDT
     VLVGCEASSS AARYGSTIDT DWSISFEQIL ASMLTETALV NYFEKKVDIG LKIKEQKKVE
     RQFSSSSDYD LSS
//