ID M7AWJ2_CHEMY Unreviewed; 564 AA.
AC M7AWJ2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Docking protein 1 {ECO:0000313|EMBL:EMP29826.1};
GN ORFNames=UY3_13045 {ECO:0000313|EMBL:EMP29826.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP29826.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SIMILARITY: Belongs to the DOK family. Type A subfamily.
CC {ECO:0000256|ARBA:ARBA00010955}.
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DR EMBL; KB553570; EMP29826.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AWJ2; -.
DR STRING; 8469.M7AWJ2; -.
DR eggNOG; KOG4047; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR CDD; cd01203; PTB_DOK1_DOK2_DOK3; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR037751; Dok1/2/3_PTB.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21258:SF46; DOCKING PROTEIN 1; 1.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR Pfam; PF02174; IRS; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS51064; IRS_PTB; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 1..100
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 136..240
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 303..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..333
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 62179 MW; 57E91A430747032E CRC64;
MQRWKKNWFV LYPASQHGVA RLEFFDCKDP GAPAEKLSTK RLDKKIIRLA DCVSVAPVPE
SGPKDSTAVF RLETSDRSYL FAAEKEQSAE WVEKLCEIAF SGNSTNGART GGSKECDGGA
PALEMAVNSI YYSREDVNDF WVTVQRTEAA ERCALQGAYL LKAEQDSLIL KEPRTQETLY
TWPYRLLRRY GRDKVMFSFE AGRRCESGPG NFTFETKQGN EIFRLVEASI REQKAQVEEN
RQSCDSLDLD CPSVVLIRNA LADSLCLELP AEGDGPTVPK AGLAAKLSSA PEERDTIALL
KARTLPEPPV PPKPAHPSTP PRSPLPKVPR AVPPSEDPAS LYSEPMDAVK GIRARVDPLY
SDPIDSKPGG GAMGHGPAQE EAKLRKPGSL YSGLYDQVQP AGNSQAERLL RCREHIYDEP
EGRAPHPVPA NASIYDEARP TGEAWRTQGI EDKGGYEYPY NPRTDDYSVP AFQHKAGSKG
PKPIPAPKPQ AVFIPKGAER SPEPSKWRVN LAPDKAGVRS GLNNNNNNNE VLYSQVLKPL
RVPGQELSVD EKALMPIYED LGEI
//
