ID   M7AXK7_CHEMY            Unreviewed;       627 AA.
AC   M7AXK7;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Apolipoprotein L3 {ECO:0000313|EMBL:EMP29494.1};
GN   ORFNames=UY3_13382 {ECO:0000313|EMBL:EMP29494.1};
OS   Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX   NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP29494.1, ECO:0000313|Proteomes:UP000031443};
RN   [1] {ECO:0000313|Proteomes:UP000031443}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
CC   -!- SIMILARITY: Belongs to the apolipoprotein L family.
CC       {ECO:0000256|ARBA:ARBA00010090}.
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DR   EMBL; KB555682; EMP29494.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7AXK7; -.
DR   STRING; 8469.M7AXK7; -.
DR   eggNOG; ENOG502RZGU; Eukaryota.
DR   Proteomes; UP000031443; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   InterPro; IPR008405; ApoL.
DR   InterPro; IPR029463; Lys_MEP.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   PANTHER; PTHR14096; APOLIPOPROTEIN L; 1.
DR   PANTHER; PTHR14096:SF28; PROTEIN CBG02395; 1.
DR   Pfam; PF05461; ApoL; 1.
DR   Pfam; PF14521; Aspzincin_M35; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Lipoprotein {ECO:0000313|EMBL:EMP29494.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT   DOMAIN          101..179
FT                   /note="Lysine-specific metallo-endopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF14521"
SQ   SEQUENCE   627 AA;  67910 MW;  F73D95673871948B CRC64;
     MNFLGIVCSN AANEKTCCSH TEYKHPLFLA LTKEKRRTAE AAKQSALEIL RDALKKNQVL
     VEKPTEWLLR NNGDPKFWML TAELVRDLIS VLEAVTFMED LSEKNIFARV YPKSEDKTIY
     LGPQFWEASK HLAKDSQPGM LIHEASHFLR TDIITYEDVS VDRRGLMETT NSMSLHNANF
     APLSGAVLNA NIEYVFELTL NHKGKYENAQ YSCCGEIARN SVCEKTVPAE FFSSPFNGSL
     SISPDIEEIL KESLLPATGR VRRLLDELQE IADAIDKIHK GATIANVAGG TVGIAGGITT
     IVGLCLAPFT FGASLIVSLT GFAVATAGGL TSAAAATTDM VASKVKKETV EKLLLECQAE
     LENIKDYTES ITEKIHRLKD YENSGFVFAF AQIGSGAGRT VLNTLKIVKA GQLLATAGRI
     ARFAGAATHI LTVVTLGLDV FFVARDSMEL HKGAKTELAA KIREAVNEME QVIGELGAAR
     CSSLVIGVPV VSAGSQRLTA SAPVSPRAGS AECKHNNPTP AIKYKPGAKS GSSVTFCWET
     HIAADLSRSF WQPQQHCLGS DPGVTHPTQR AQCREHSSTK KPGVNACSEK GPFQQTCPYT
     GLCLRPVGTG SRPLMQPCEQ RHGEPRG
//