ID M7B2U4_CHEMY Unreviewed; 815 AA.
AC M7B2U4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=DENN domain-containing protein 1B {ECO:0000313|EMBL:EMP32216.1};
GN ORFNames=UY3_10646 {ECO:0000313|EMBL:EMP32216.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP32216.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB541574; EMP32216.1; -; Genomic_DNA.
DR AlphaFoldDB; M7B2U4; -.
DR STRING; 8469.M7B2U4; -.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 6.10.140.1000; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR040032; DENND1A/B/C.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR13196:SF24; DENN DOMAIN-CONTAINING PROTEIN 1B; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 114..459
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 89..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 815 AA; 90446 MW; 7262BC7645AE22F4 CRC64;
MPGSPGLKKC GSCNESVLRS DGHSLCVKCL GETHIPAKCV HCNSLKSRAS CGRDLQLKML
LMEKSLQPPA ETGMSKRFPS CFPARSELTR STASPSHAKR QDAPTSPHRD LNKRKRSPAK
SLPPVLTAPK TGTDDCPSTS GTAHEVLQSV PKFCFPFDVE RVSQNQVGQH FTFVLTDIES
KQKFGFCRLT SGGKVCLCIV SYLPWFEVYY KLLNTLADYL AKEQENDLND MLKSLYSHPV
PKANTPVSLN VRNLTEYFVA VDVNNMMQLY ASMLHERRII ITSSKLSTLT ACVHGSAALL
YPMYWQHIYI PVLPPHLLDY CCAPMPYLIG VHLSLIERVK NRSLEDVVML NVDTNTLENP
FNDLNNLPSE VVSALKNKLK KQSTATGDGV ARAFLRTQAA LFGSYRDALR YKPGEPITFC
EDSFVKHRSS TTKQFLETAV NLQLFKQFID GRLSKLNAGR GFSDVFEEEI TSGGFCGGNS
RSYQQWVHTV KESDEEYGTC SSGVLQCAPV YTLHNQKRGN SEKRRLAQTR FNQHLANVSN
HDSALDDDDD DEMDRTSKLS SEDSEEASAY FYDSDDSGET GVMSYHTGEM DLLGEILDTL
STHSSDQGKL SGAKSLDFFR STDDIDYKAM NKSSAPSESN LALLCSGTND PVEWNLGQDD
SVLHGKQLPP SPRKQVDFSD HMESVSVLQE ENSDKTLSAD HVDFPKDFVK SASPTRSVAQ
LASLEFSQVE DSFHRKIKPN ETLSNTSEDQ LPVNLCQHPS ILIPWQKDGD EGKETPEESG
LLHEVVSLCK VTSAFHHSLN ISEDNYSSNS SGNKA
//
