ID M7B655_CHEMY Unreviewed; 914 AA.
AC M7B655;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=FH1/FH2 domain-containing protein 1 {ECO:0000313|EMBL:EMP27643.1};
GN ORFNames=UY3_15269 {ECO:0000313|EMBL:EMP27643.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP27643.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB568448; EMP27643.1; -; Genomic_DNA.
DR AlphaFoldDB; M7B655; -.
DR STRING; 8469.M7B655; -.
DR eggNOG; KOG1925; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 2.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR041387; FHOD1_GBD_N.
DR InterPro; IPR014768; GBD/FH3_dom.
DR PANTHER; PTHR45920:SF2; FH1_FH2 DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR Pfam; PF02181; FH2; 2.
DR Pfam; PF18382; Formin_GBD_N; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 1..395
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT REGION 271..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 755..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..849
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 914 AA; 101195 MW; 4CA5061D36F09E7A CRC64;
MGGPLCLQLA DCTLQVSPSG QYLDLDLSLL EQKDELEGFY EEISKGRRPT LILRTQLSVR
VHAILEKLYN SQGPELRRSL FSLKQLFQED KDLVPEFVNL EGLTCLIKVG AEADQNYQNY
ILREFVDGML GVIAHNETVQ WLYTLCGSMY RLVVKTALKL LLVFVEYTES NAQLLIQAVN
TVEQARDAYP WSNLVAILEE RNGADTELLV FAMTLINKTL AALPDQDSFY DVTDCLEQQG
MERIVQRHMR GKGLDPDVKQ QFAVYESSLK HEDGVEELPP GARKERRKTD ENRRGRRSLG
GNVDAGAGAS SPSPAVEDNK LPEPSSPPRE PTAEVVLESS PAPPRFESVY NSTSNVRLSA
LASPEEREHP SLGERSVFKA RFLENLASSQ KERLSAMSKG RLDILAEAIP GGGQLSLEPP
PAAAPAKKKK TVKLFWKELK HHSSHAGAGR FGRGTVWASL ERVEIDAAKL EHLFESRAKE
VLSSKKAADG KKCTVVLDPK RSNAINIGLT VLPPVHIIKT AILSFDEFAI NKEGIEKILS
MVPTDEEKQK IQEAQLTNPD VPLGSAEQFL LTLSSISELT ARLQLWAFKL DYESMEQSRG
FELSYLEKVS EVKDTVHRQS LLHHLCYTVV ERFPQTSDLY SEIAAITRSA KVDFDELAES
LNQLERRCKA SWDSLKAITK HETKPGLKSK LTDFLKDSSR KIHVLKVVHR RVLHRSVCLL
GADPLVLVRL PWQGGGPMGF ALEYRTCRER VLQQQRKRAA HRERNKTRGR MITEVRGCPG
GRGGPEASPS PAVGAASPEQ RGDAGHETMK SVLSSAAEPH SRRSRASRGM GRSSPSGGSV
PQEDSSGSAA DASDEIMDRL VQSVTHSTGP RPGAARERKR SRVSRKSLRR TLKSGLSDDL
VQALGLAQTP GLEV
//
