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Database: UniProt
Entry: M7BBS0_CHEMY
LinkDB: M7BBS0_CHEMY
Original site: M7BBS0_CHEMY 
ID   M7BBS0_CHEMY            Unreviewed;       359 AA.
AC   M7BBS0;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   03-JUL-2019, entry version 38.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 1 {ECO:0000313|EMBL:EMP29598.1};
GN   ORFNames=UY3_13256 {ECO:0000313|EMBL:EMP29598.1};
OS   Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudines; Cryptodira; Durocryptodira; Americhelydia;
OC   Chelonioidea; Cheloniidae; Chelonia.
OX   NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP29598.1, ECO:0000313|Proteomes:UP000031443};
RN   [1] {ECO:0000313|Proteomes:UP000031443}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z.,
RA   Li C., White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y.,
RA   Zheng Y., Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M.,
RA   Li Q., Wang J., Zhang H., Yu L., Shigenobu S., Wang J., Liu J.,
RA   Flicek P., Searle S., Wang J., Kuratani S., Yin Y., Aken B., Zhang G.,
RA   Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield
RT   insights into the development and evolution of the turtle-specific
RT   body plan.";
RL   Nat. Genet. 45:701-706(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KB555015; EMP29598.1; -; Genomic_DNA.
DR   RefSeq; XP_007066421.1; XM_007066359.1.
DR   STRING; 8469.XP_007066421.1; -.
DR   GeneID; 102944012; -.
DR   KEGG; cmy:102944012; -.
DR   CTD; 3758; -.
DR   KO; K04995; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000031443; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003268; K_chnl_inward-rec_Kir1.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF6; PTHR11767:SF6; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000031443};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:EMP29598.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     64     86       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    126    148       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       24    152       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      160    331       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        139    139       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   359 AA;  41146 MW;  471A2F2C753281FF CRC64;
     MFKYFRKRFA SHLTERCRRR ARLVSKDGRC NIEFGNVEEQ SRFVFLIDIW TTILDLRWRY
     KMTIFISAFL GSWFLFGLLW YVVAYIHKDL PEFSPSINHT PCVQNINGLT SAFLFSLETQ
     VTIGYGFRYV TAILGVIINS FMCGAILAKI SRSKKRAKTI TFSKNAVISK RGGKLCLLIR
     VANLRKSLLI GSHIYGKLLK TTITPEGETI ILDQVNIDFV VDAGNENLFF ISPLTIYHII
     DKTSPFFHMS VETILQQDFE LVVFLDGTVE ATSATCQVRT SYIPEEVLWG YRFAPIVSKT
     KEGKYRVDFH NFSKTVEVET PHCAFCLYNE KDAKAKAKRG YDNPGFILSE VNETSDTKM
//
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