ID M7BH37_CHEMY Unreviewed; 705 AA.
AC M7BH37;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=UDENN domain-containing protein {ECO:0000259|PROSITE:PS50211};
GN ORFNames=UY3_07964 {ECO:0000313|EMBL:EMP34930.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP34930.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Recycling endosome
CC {ECO:0000256|ARBA:ARBA00004172}.
CC -!- SIMILARITY: Belongs to the DENND6 family.
CC {ECO:0000256|ARBA:ARBA00007159}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290}.
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DR EMBL; KB530910; EMP34930.1; -; Genomic_DNA.
DR AlphaFoldDB; M7BH37; -.
DR STRING; 8469.M7BH37; -.
DR eggNOG; KOG0070; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR CDD; cd04150; Arf1_5_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045872; Arf1-5-like.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR024224; DENND6.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR037516; Tripartite_DENN.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR13677:SF1; PROTEIN DENND6A; 1.
DR PANTHER; PTHR13677; UNCHARACTERIZED; 1.
DR Pfam; PF00025; Arf; 1.
DR Pfam; PF02141; DENN; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS50211; DENN; 1.
PE 3: Inferred from homology;
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 44..487
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
SQ SEQUENCE 705 AA; 80794 MW; CA882D5FF72ADB5A CRC64;
MAVREQSQSG ALSAASRSPC EAEEAALGRC LSLLPWDRFS AWLHCVCVVG FDLELGQAVE
IRPNFCAANI HATSVCDVPC LGSEKDEAHL VIERETNENP GFYCYRKPVF AICLFQIPIQ
KDPAYYYGYV YFRQVRDKTL KRGYFQKSLV LISKLPYIHL FHTVLRHIAP EYFEKNEPFL
EAVCSDVDHW PPPVPGKTLN LPIMGIIMKV RIPTCHDKPG TTHIVQFTHQ EDTQISIALP
TVHEVDLFKC FCPVFFHIQM LWELVLLGEP VVVMAPSPSE SSETVLALVS CISPLKYCSD
FRPYFTIHDS EFKEYTTRTQ APPSVILGVT NPFFAKTLQH WPHIVRIGEI KLPGEVPKQV
KVKKLKNLKT LDSKPGVYTS YKPYLNRDEE IIKQLQKVNL QICLLKLFCM LVDLFLRIWV
VKHFLKSPNF SGWFRTRRKE MTQKLEALHL EALCNEDLLL WSQKHTEVET VDLVLKLKNK
LFQADREHLP MKPDTMEKLQ MHIDAIILAL PDDLQDILLK TARAAMGLTI SSLFSRLFGK
KQMRILMVGL DAAGKTTILY KLKLGEIVTT IPTIGFNVET VEYKNICFTV WDVGGQDKIR
PLWRHYFQNT QGLIFVVDSN DRERIQEAAE ELQKMLQEDE LRDAVLLLFA NKQDLPNAMA
ISEMTDKLGL QSLRNRTWYV QATCATQGTG LYEGLDWLSN ELSKR
//
