ID M7BMH1_CHEMY Unreviewed; 1335 AA.
AC M7BMH1;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=E3 ubiquitin-protein ligase SHPRH {ECO:0000313|EMBL:EMP39096.1};
GN ORFNames=UY3_03670 {ECO:0000313|EMBL:EMP39096.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP39096.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB517583; EMP39096.1; -; Genomic_DNA.
DR STRING; 8469.M7BMH1; -.
DR eggNOG; KOG0298; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd18070; DEXQc_SHPRH; 1.
DR CDD; cd00073; H15; 1.
DR CDD; cd15547; PHD_SHPRH; 1.
DR CDD; cd16569; RING-HC_SHPRH-like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048695; SHPRH_helical_2nd.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45865:SF1; E3 UBIQUITIN-PROTEIN LIGASE SHPRH; 1.
DR PANTHER; PTHR45865; E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00538; Linker_histone; 1.
DR Pfam; PF21324; SHPRH_helical-2nd; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00526; H15; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51504; H15; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 365..439
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT DOMAIN 1142..1189
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 1224..1335
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 437..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1335 AA; 151732 MW; 75A9D5B18D4DBC2F CRC64;
MSSRRKCAPP LRMDEEKKKQ LCWNMHEDRR NEVIILDDNI DEDNPVPGPS TSSVSFVIDD
DSIDEGLSYK ENGGSKSVGF STDEGEDSCS ILTSISVQLN IVVSPYHSDN SWKALLGEFV
LQLLLEKILI EKIHKRSFTL MRADSGDQLQ ICVHARNGEE GGDEEEESLG DYEEGILVES
SLSSETLEDL RWLQKKKVIG LYQRPREDQA LKVGIYLLEA GLSKSEFLSD GGGRVKKANQ
LIQKLMEKYY NFIIPENTLH FLWREVITPD GVKLYYNPFT GCIIREHPVA GPPWPGGILA
DEMGLGKTVE VLALILTHTR RDVKQDVLTL PEGKLVNFFV PPQPTEGNKK KKAKKVELKS
KEKVQYPSLR VMILAAVKEM NVKKGASIVA IFKYVSAIYR YDIQRNRRLL KRTLEKLIAE
QVVEQVKGHG LAGSFKLGKN YKEQKRHERT KKQTTRSPGR IQKTSLPNAK TQTKESASRV
TSSEKVKPPR LVDIPAEEHD YCTTSKNNKK SETGQRTCIK EENLQPRVMD LESADLQGDL
MFSDSTSPVL SACKNTDDVE VLKDQSSDSQ ECAGSVIQHA SSIFPFNTSD YRFECICGEL
GLVDCKARVQ CLKCHLWQHA ECVNYKEENL KIKPFYCPHC LVAMKPVSTG ATLIISPSSI
CHQWVDEINR HVRSSSLQVL VYQGVKKHGF LQPHMLAEQE VVITTYDVLR TELNYVDIPH
SNSEDGRRFR NQKRYMAIPS PLVAVEWWRI CLDEAQMVEC TTAKAAEMAL RLSGINRWCV
SGTPVQRGLE DLYGLVLFLG VDPYWVKHWW DQLLYRPYCR KNPQPLYSLI ANIMWRSAKK
DVIDQHSGSL WWLDVIQTAI QYAIDEELVQ RVQNEITSNY KQQTNKLSMA DKFRDCRGLQ
YLLTTQMEEV KKFQKLVREA VKNLEGPPSK KVIEAATLCH LRPVRLPLNN CVFCKADELF
TEYESKLFSH TVKGQMAIFE EMIEDEDGLV DDRLPTTSRG LWAASETERS LKAILSFAKA
HRMDVRLIEE GNIFLELFEA WKKEYKLLHE YWMVLRDHVS AIDELAMATE RLRVRHPDEP
KPSPPVLHII EPHEVEQNRV KLLNDKAVAK SQLQKKLGQL LYLTNLEKSQ DKTTGGVNPE
PCPICARQLG KQWAVLTCGH CFCNECIAII IEQYSVGTRR SSIKCAICRQ TTSHKEISYV
FTAETANQED DIPVKGSHST KVEAVVRTLK KIQFKDPGAK SLVFSTWQDV LDIISKALDD
NNMVFAQING ISKFQENLSA FKYDPKINIL LLPLHTGSNG LNIIEATHVL LVEPILNPAH
ELQAIGRVHR IGQTK
//
