ID M7BPP0_CHEMY Unreviewed; 222 AA.
AC M7BPP0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Cystatin domain-containing protein {ECO:0000259|Pfam:PF00031};
GN ORFNames=UY3_03589 {ECO:0000313|EMBL:EMP39219.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP39219.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the cystatin family.
CC {ECO:0000256|ARBA:ARBA00009403}.
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DR EMBL; KB517361; EMP39219.1; -; Genomic_DNA.
DR AlphaFoldDB; M7BPP0; -.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR PANTHER; PTHR47033; CYSTATIN-M; 1.
DR PANTHER; PTHR47033:SF1; CYSTATIN-M; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
PE 3: Inferred from homology;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022704};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Thiol protease inhibitor {ECO:0000256|ARBA:ARBA00022704}.
FT DOMAIN 154..197
FT /note="Cystatin"
FT /evidence="ECO:0000259|Pfam:PF00031"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 222 AA; 24578 MW; A7E33316D8C7EAC3 CRC64;
MAHGRSFRRA YSLRTPKSPS LLDSTYGRLE DTTLPHVWGD KTESSDKSKQ RRKGRAVSLR
GWKSGVEEPP AERTLTPGEM PHSLSPDDGE LLIGEAQSKG SHRMKQCKKG GEGGHCIATL
SSALLLTAAL PSELGIQPVA AALWLPSSED YAKNVPVSDP EVQKAAQVAV KTFNDRTNCA
YYSQVRRVLS AQRQIVRCEF QIWSQPWLNR PEIDFRCNSG DD
//
