ID M7BW42_CHEMY Unreviewed; 449 AA.
AC M7BW42;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Rho guanine nucleotide exchange factor 19 {ECO:0000313|EMBL:EMP42071.1};
GN ORFNames=UY3_00661 {ECO:0000313|EMBL:EMP42071.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP42071.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB478633; EMP42071.1; -; Genomic_DNA.
DR AlphaFoldDB; M7BW42; -.
DR STRING; 8469.M7BW42; -.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR047271; Ephexin-like.
DR PANTHER; PTHR12845:SF2; DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 341..449
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 119..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 166..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 50191 MW; CD37CEB445E60B00 CRC64;
MALSHPTFHL CGCPRWLTCL PGPAHFISRL PLHHRLGYLR LSRENEHLGK NKPWLRHLIA
PMDFFCRKRA RSDSPPRAVA LVKRHGSCPV AQSPQPARPE SRLELGPFLA GLFRPRSAQK
GLSAARRGGS RDPGSAAEER VPLLVDNSKG ADLPGSAVPV PLHCQPSPPT AELAALESTG
PKEPVEEPPS FAGPTGPAGL LEMRTKQPTP IPGRKVLHGS LEDLSKATAM QMPSPESRLF
RRPLGKGAKD TDKWRRESKY VQTQPLYQDY WMKRLKAVER KPKEPSFRVD ASLSIAGILS
SSLLGAASQI SSRDYSFCFW QEIPEVKSGR LLESLTPQQH HLQEAMFEMI TSEASYLCSL
SVAMSHFKGS LALRETLTRA EVHRLFSNLQ QVKDISERFL LDLEEHMDKD VFLTGLGAVV
LKHCPAFHRV YIPYVTNQMY QEQLMQQLM
//
