ID   M7C280_CHEMY            Unreviewed;      1565 AA.
AC   M7C280;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Adenylate cyclase type 10 {ECO:0000313|EMBL:EMP34522.1};
GN   ORFNames=UY3_08351 {ECO:0000313|EMBL:EMP34522.1};
OS   Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX   NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP34522.1, ECO:0000313|Proteomes:UP000031443};
RN   [1] {ECO:0000313|Proteomes:UP000031443}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
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DR   EMBL; KB532022; EMP34522.1; -; Genomic_DNA.
DR   STRING; 8469.M7C280; -.
DR   eggNOG; ENOG502QPPT; Eukaryota.
DR   Proteomes; UP000031443; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 3.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT   DOMAIN          41..165
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   1565 AA;  179444 MW;  83A3B6338016C147 CRC64;
     MEQRKSSDSS IIGKVAAHVP DLIVYGDFSQ EVPFIESFDG VLLFADISGF TALTEKFSMD
     TSLDRGADQL TQTLNHYVGD IVEGDALLAL WKVQRSQLSD IITLALKCSL RIQEEYGVRE
     TEVGLELRVK IGLSAGHISK VVVGDNKHQY FLVIGRAVDE VRLAQNLAKA SEVILSPNCW
     ELCNRNMIEI ERIKDQRAVK ARYIKNISET EFDEFFWKCT EYLQNYPTGE SNSILRETST
     LSPNDELEKS LRKFVMRNIL KKIDDNQPLE YLSELRPVTI VFVNLQFDES ANTLHLCKAI
     HNANMKISDT IHVFSGKINK VFMFDKGCTF LCVFGLPGDK QADESTHALD SAFKIFNFFI
     GQKVNLAARM MMYYPGLVSC DAVTYANSRL PHYFFEELPQ TEMKGVVNPG VVYHYLGISE
     KTMIGKAYLT KERSECYPLL GREKELEIYD TLLKGFVGST EGRIIMYEGL MGYGKSQLLA
     EIAYLGQKAG HRVVAMELTK INVQQNFFAI RTLMAMFLGI DACKSYDARQ HILQGKLRGV
     VEQTYYCLLN NIFLVKAVEK DILIFVIDEA HFIDPASWEF LDNLLSSIPV FMVMSLAPFS
     CQARLPCVSA ASIINNAKTI YVQLQELKPS VILQKACQDL GVVSIPRELE TFLIQRSHGI
     PFYCEELLRN LHLNNMLIFH LWEEEEEVDD EWEILFTNAI KVIPSKTESL SSLDNDLYIC
     TIRQNVKLQN IMLPPTLKGI ALAELDNMSP SEQMVVKCAA IIGLTFTTEL LLHILPEWTK
     RKMNQTLAAL VDSHIFKCFN KRKDSQNAQS QDMPSIELLV CRGMVRSTGQ ESDIRSSVYN
     RIKQEQLVMQ CSIMAFCTPL LQEAAYEVWL KSQKKALHLK CVSYLEGQAH KCRRCGEGDF
     ISFHRHTVEM ILVNTGSQED ISEQHKEYPF SEAASLIIKT TLKNLQAPSF EGDGEKAPSQ
     GAIDYGPAPQ RAEEIEKEFL ERLDEIIQHS DRDQEKIRRL GSCKCEEIVE SVFVPLARHC
     MAMGEYARAL YYLLECAAAY LHLSNNYMAF CNLNTAENLI KSVDFRATVI NQFEEATFYS
     LKGEVCYNMG QMNLAKKFIR KALILLNRRF PFTLIGVFFK TLVEVSKHAS HQKKQQFLYS
     RSKGEKKLAF LYQQGHCLSL LWQLFSLDTA TNSKKFCRLA ALMKVNSAEE SEDESQIISS
     YTEFSLCCQM MGYQDEWMKY ELMAIQRSSH LQVIGGGLLT TVKLAQSLAY MKLCLGNLPL
     SIQLGYRAHE MCVRLKKPKL DYLVLCMLFK ALFLSIRYQD CVRVLSWMEE LVVKEERIIG
     MAYFFSYCLE LLLYAGFSFK SFKECLEFIQ RNEKNCILMS QNSIMLGLYS SLAIWFARLH
     QWGNFKEPFE KARRLLRRTN ASFFAISGFC RFLECEVLVL RKHIEEKPES VRDTRTKTLK
     DLDQVLSRCS TSPIYYPRVY HLKAYTFLVL GSEEQSQIYL SKAFKLCDIY GNLLEKSWLE
     ISNEWWFTGK DPMEDLWLKA APDFPKWEIG MTEEDFPEIH KTKYLLRVPV LDINNPFPEP
     EIPDV
//