ID M7C4W5_CHEMY Unreviewed; 1150 AA.
AC M7C4W5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Protein flightless-1 like protein {ECO:0000313|EMBL:EMP35542.1};
GN ORFNames=UY3_07308 {ECO:0000313|EMBL:EMP35542.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP35542.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB528467; EMP35542.1; -; Genomic_DNA.
DR AlphaFoldDB; M7C4W5; -.
DR STRING; 8469.M7C4W5; -.
DR eggNOG; KOG0444; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd11280; gelsolin_like; 1.
DR CDD; cd11290; gelsolin_S1_like; 1.
DR CDD; cd11292; gelsolin_S3_like; 1.
DR CDD; cd11288; gelsolin_S5_like; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.20.10; Severin; 6.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007122; Villin/Gelsolin.
DR PANTHER; PTHR11977:SF139; PROTEIN FLIGHTLESS-1 HOMOLOG; 1.
DR PANTHER; PTHR11977; VILLIN; 1.
DR Pfam; PF00626; Gelsolin; 2.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 2.
DR PRINTS; PR00597; GELSOLIN.
DR SMART; SM00262; GEL; 6.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00369; LRR_TYP; 8.
DR SUPFAM; SSF55753; Actin depolymerizing proteins; 6.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 447..527
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT DOMAIN 667..736
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 346..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..874
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..890
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1150 AA; 131124 MW; 507887CA2C4A0171 CRC64;
MPAKAMILQG PKLVHDVSLM GAAPSKPAIV ARANSLKNSG VPDDIFQLDD LSVLDLSYNQ
LTECPRELEN AKNMLVLNLG HNSIDNIPNQ LFINLTDLLY LDLSENTLES LPPQMRRLVH
LQTLILNSNP LLHAQLRQLP AMTALQTLHL RNTQRTQSNL PTSLEGLINL ADVDLACNEL
SRVPECLYTL SSLRRLNLSS NQISELSLCI DQWTQLETLN LSRNQLTSLP SAICKLTKLK
KLYLNSNKLD FDGIPSGIGK LTSLEEFMAA NNNLELIPES LCRCTKLKKL VLNKNRLVTL
PETIHFLTDV EVRTRRDGPL CFAGARWADA RGPVLPWEPV PGGSMHPRAV WAGSGTKDPT
ARKTRLRRRK ASAGQDDQAK QVLKGMSDVV EEKNKKLEEN GDMKYTDPKT RRWDQSLEKP
QLNYSEFFTE DVGQIPGVSV WQIENFVPTL VDEAFNGKFY EADCYIVLKT FLDDNGSLTW
EIYYWIGQEA TLDKKASAAI HAVNLRNYLG AECRTVREEM GDESEEFSQV FDHEISYIEG
GSASGFYTVE DAQYITRLYR IYGKKNIKLE PVTLKAASLD PRLFAEKINK NERKGKAEIT
LLSQSQEPPE FWEVLGGQPE EIKANVPDDF QPAKPKLYKV GLGLGYLELP QINYKLSVEH
QKRPKVDLLP EMRLLQSLLD TKAVYILDCW SDVFIWVGRK SPRLVRAAAL KLGQELCSML
HRPKHAMVIR NLEGTECQVF KSKFKNWDDV LKVDYTRNAE SVLQAKGLAG KVKKDTEKKD
QMKADLTALF LPRQPPMALT EAEQLMEEWN EDLDGMEGFV LEGKKFARLP EEEFGHFHTQ
DCYVFLCRYW VPVEYEDEAE EKKKKKSGGK GAGEGGEDEE EEEEEEKQPE EDFQCIVYFW
QGREASNMGW LTFTFSLQKK FESLFPGKLE VVRMTQQQEN PKFLSHFKRK FIIHKGKRKS
KDNNPQPSLY HVRTNGSALC TRCIQINTDS CLVPFESTDN QGIVYTWVGR AADPEEAKLA
EDIMNHMFDD SYSKQVINEG EEPENFFWVG IGGQKAYDED ADYMKYSRLF RCSNEKGYFA
VSEKCSDFCQ DDLADDDIML PANGREVYIQ HMRSKAAEHP RKLRLVRKGN EPHPFTRCFH
AWGVFRKPPA
//
