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Database: UniProt
Entry: M7CM00_CHEMY
LinkDB: M7CM00_CHEMY
Original site: M7CM00_CHEMY 
ID   M7CM00_CHEMY            Unreviewed;       645 AA.
AC   M7CM00;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   05-JUN-2019, entry version 35.
DE   SubName: Full=Disintegrin and metalloproteinase domain-containing protein 9 {ECO:0000313|EMBL:EMP42217.1};
GN   ORFNames=UY3_00605 {ECO:0000313|EMBL:EMP42217.1};
OS   Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudines; Cryptodira; Durocryptodira; Americhelydia;
OC   Chelonioidea; Cheloniidae; Chelonia.
OX   NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP42217.1, ECO:0000313|Proteomes:UP000031443};
RN   [1] {ECO:0000313|Proteomes:UP000031443}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z.,
RA   Li C., White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y.,
RA   Zheng Y., Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M.,
RA   Li Q., Wang J., Zhang H., Yu L., Shigenobu S., Wang J., Liu J.,
RA   Flicek P., Searle S., Wang J., Kuratani S., Yin Y., Aken B., Zhang G.,
RA   Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield
RT   insights into the development and evolution of the turtle-specific
RT   body plan.";
RL   Nat. Genet. 45:701-706(2013).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR   EMBL; KB477522; EMP42217.1; -; Genomic_DNA.
DR   Proteomes; UP000031443; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   CDD; cd04269; ZnMc_adamalysin_II_like; 1.
DR   Gene3D; 3.40.390.10; -; 2.
DR   Gene3D; 4.10.70.10; -; 1.
DR   InterPro; IPR006586; ADAM_Cys-rich.
DR   InterPro; IPR018358; Disintegrin_CS.
DR   InterPro; IPR001762; Disintegrin_dom.
DR   InterPro; IPR036436; Disintegrin_dom_sf.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   InterPro; IPR034027; Reprolysin_adamalysin.
DR   Pfam; PF08516; ADAM_CR; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 2.
DR   PRINTS; PR00289; DISINTEGRIN.
DR   SMART; SM00608; ACR; 1.
DR   SMART; SM00050; DISIN; 1.
DR   SUPFAM; SSF57552; SSF57552; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS00427; DISINTEGRIN_1; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000031443};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00068,
KW   ECO:0000256|SAAS:SAAS00117091};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Integrin {ECO:0000313|EMBL:EMP42217.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    541    561       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       93    255       Peptidase M12B. {ECO:0000259|PROSITE:
FT                                PS50215}.
FT   DOMAIN      263    349       Disintegrin. {ECO:0000259|PROSITE:
FT                                PS50214}.
FT   DOMAIN      485    519       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   REGION      576    604       Disordered. {ECO:0000256|MobiDB-lite:
FT                                M7CM00}.
FT   REGION      623    645       Disordered. {ECO:0000256|MobiDB-lite:
FT                                M7CM00}.
FT   COMPBIAS    583    604       Polar. {ECO:0000256|MobiDB-lite:M7CM00}.
FT   DISULFID    321    341       {ECO:0000256|PROSITE-ProRule:PRU00068}.
FT   DISULFID    509    518       {ECO:0000256|PROSITE-ProRule:PRU00076}.
SQ   SEQUENCE   645 AA;  70995 MW;  8BB4DA756A4E2D46 CRC64;
     MLALSTCDGL RGILHIGDKQ YGMEPVDTSA TFEHLFYPLE HVQQDPFLCG VLNDNLHQEK
     SVKNSLRYTN VSHSSFSREK LFRKKRAVLP QRRYVELFMV VDNNRYLQKN SDPVAVQKET
     IELINYVDMM YDALNIQIVL IGLEIWSDKN HINVMDGGRS AYSGAVGMAF VSTVCSQVHG
     GSISTLKGNN VQRHATVVAH ELGHNLGMKH DDGRCSTSYI MYSTDNGSKN FSTCSANDFE
     KLILNGGGNC LKNAPKPSDI FTEPFCGNNM VDKNEECDCG KPQECTNPCC DAVTCKFKSG
     SQCAEGLCCE NCKFKVAGVE CRPKMNFCDL PEYCNGTYPY CPDDVYIMNG YPCNNMKEYC
     YSGVCQNFDS QCESIYGQGA RKAPDICFEV ANLKGDRFGN CGMSSGTYNK CPIEHSLCGK
     LQCTSVSLEN LPASSVVSNQ DGVSCVTSDF DLGSDIPDPA QVQKGTACGK GKACVDFKCV
     NASELGYNCD VMQKCNNRAV CNNNGNCHCN PGWAPPFCDK SGYGGSIDSG PTHIDTSLRD
     GLLVFFLLVL PVLIAVIIAF IKRDAIKRRF CRKSRRRYRD NNTQQPKQNN GPNQNNAINN
     PFHPHEWSTM SVQGSINTAK FAGSGSMSEY TQSPTAMGGD DNQLL
//
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