ID M7N820_9BACT Unreviewed; 455 AA.
AC M7N820;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN Name=norM {ECO:0000313|EMBL:EMR03402.1};
GN ORFNames=ADICEAN_01424 {ECO:0000313|EMBL:EMR03402.1};
OS Cesiribacter andamanensis AMV16.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cesiribacteraceae;
OC Cesiribacter.
OX NCBI_TaxID=1279009 {ECO:0000313|EMBL:EMR03402.1, ECO:0000313|Proteomes:UP000011910};
RN [1] {ECO:0000313|EMBL:EMR03402.1, ECO:0000313|Proteomes:UP000011910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AMV16 {ECO:0000313|EMBL:EMR03402.1,
RC ECO:0000313|Proteomes:UP000011910};
RX PubMed=23682146;
RA Shivaji S., Ara S., Begum Z., Srinivas T.N., Singh A., Kumar Pinnaka A.;
RT "Draft Genome Sequence of Cesiribacter andamanensis Strain AMV16T, Isolated
RT from a Soil Sample from a Mud Volcano in the Andaman Islands, India.";
RL Genome Announc. 1:E00240-13(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR03402.1}.
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DR EMBL; AODQ01000026; EMR03402.1; -; Genomic_DNA.
DR RefSeq; WP_009194824.1; NZ_AODQ01000026.1.
DR AlphaFoldDB; M7N820; -.
DR STRING; 1279009.ADICEAN_01424; -.
DR PATRIC; fig|1279009.4.peg.1442; -.
DR eggNOG; COG0534; Bacteria.
DR OrthoDB; 9780160at2; -.
DR Proteomes; UP000011910; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd13131; MATE_NorM_like; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011910};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 455 AA; 49207 MW; 6DD6EAF10188CCE9 CRC64;
MLAAQPTTTA FGWQARRLLQ IALPVMLSYL GHVLVGTADS MMVGQLGKVP LAAVSLANSI
VVLPMMFGLG LSYGLTPLVA SADGQGNTRR IAKLLQHSLL INLGAGVALA GLSLLVLPFL
DEMNQPPDVV AIVGPYLAIV AFSLVPLMLF QAFKQFAEGL GFTRKAMYIT LAANGVNIFF
NWVLIYGKLG FPAMGLEGAG WSTLFARVMM VLGMGYYCYR SPRFAPYRAL FGLKRFKRKL
SLRLMQLGIP MGLQFVFEVG AFSGAVIMAG WMGDTQQAAH QIAINLASMS YMIASGISAA
ATVQVGNLLG RKDLPGVRMA GITATVLVLG LQTLFAFIFL FGRYLLPTFY IDNEQVIEVA
AGLLVIAAFF QLSDGVQVVG LGALRGMEDV RIPTWITLFA YWVLALPLGY VLGFVFDMGI
NGVWWGLLTG LTVAAVLLAV RFWRKTQQLP QKVVQ
//
