ID M7NSV5_PNEMU Unreviewed; 394 AA.
AC M7NSV5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Ribonucleoside-diphosphate reductase small chain {ECO:0000313|EMBL:EMR10357.1};
GN ORFNames=PNEG_01610 {ECO:0000313|EMBL:EMR10357.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR10357.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SIMILARITY: Belongs to the ribonucleoside diphosphate reductase small
CC chain family. {ECO:0000256|ARBA:ARBA00009303}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR10357.1}.
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DR EMBL; AFWA02000004; EMR10357.1; -; Genomic_DNA.
DR RefSeq; XP_007873567.1; XM_007875376.1.
DR AlphaFoldDB; M7NSV5; -.
DR STRING; 1069680.M7NSV5; -.
DR GeneID; 19895305; -.
DR VEuPathDB; FungiDB:PNEG_01610; -.
DR eggNOG; KOG1567; Eukaryota.
DR HOGENOM; CLU_035339_2_1_1; -.
DR OMA; KVGEYQR; -.
DR OrthoDB; 5487627at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd01049; RNRR2; 1.
DR Gene3D; 1.10.620.20; Ribonucleotide Reductase, subunit A; 1.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR012348; RNR-like.
DR InterPro; IPR033909; RNR_small.
DR InterPro; IPR030475; RNR_small_AS.
DR InterPro; IPR000358; RNR_small_fam.
DR PANTHER; PTHR23409; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; 1.
DR PANTHER; PTHR23409:SF18; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2; 1.
DR Pfam; PF00268; Ribonuc_red_sm; 1.
DR SUPFAM; SSF47240; Ferritin-like; 1.
DR PROSITE; PS00368; RIBORED_SMALL; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958}.
FT COILED 15..45
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 394 AA; 45538 MW; 5944CF0CF5B17549 CRC64;
MEHELTPSKK VAEGILELNL TKEELEAAKN AKETLIKLKI KARKNKSDIN GSDLEENALN
IMEEEPLLME NKKRFVLFPI KYHEIWQMYK KAEASFWTTE EIDLSKDLHD WDKKLNDDER
FFISHVLAFF AASDGIVNEN LLERFSNEVQ VPEARCFYGF QIMMENIHSE TYSLLIETYI
RDPGQKKFLF DAIETIPSIK LKADWALRWI ADEHSTFAER LVAFAAVEGI FFSGSFASIF
WLKKRGLMPG LTFSNELISR DEGLHTDFAC LLFSHLRKRP SKETIQAIIV EAVSIEQDFL
TSSLPCPLLG INARLMKQYI EFVADRLLVA LGNNKYYNVT NPFDFMENIS LQGKTNFFEK
RVSDYQKSGV MASIKKQSDF ELIDGHVFSV DEEF
//
