ID M7P0E7_9GAMM Unreviewed; 266 AA.
AC M7P0E7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Spermidine synthase {ECO:0000313|EMBL:EMR12952.1};
GN ORFNames=MPL1_07378 {ECO:0000313|EMBL:EMR12952.1};
OS Methylophaga lonarensis MPL.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=1286106 {ECO:0000313|EMBL:EMR12952.1, ECO:0000313|Proteomes:UP000012019};
RN [1] {ECO:0000313|EMBL:EMR12952.1, ECO:0000313|Proteomes:UP000012019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MPL {ECO:0000313|EMBL:EMR12952.1,
RC ECO:0000313|Proteomes:UP000012019};
RX PubMed=23661481;
RA Shetty S.A., Marathe N.P., Munot H., Antony C.P., Dhotre D.P.,
RA Murrell J.C., Shouche Y.S.;
RT "Draft Genome Sequence of Methylophaga lonarensis MPLT, a Haloalkaliphilic
RT (Non-Methane-Utilizing) Methylotroph.";
RL Genome Announc. 1:E00202-13(2013).
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR12952.1}.
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DR EMBL; APHR01000037; EMR12952.1; -; Genomic_DNA.
DR RefSeq; WP_009726464.1; NZ_APHR01000037.1.
DR AlphaFoldDB; M7P0E7; -.
DR STRING; 1286106.MPL1_07378; -.
DR PATRIC; fig|1286106.3.peg.1480; -.
DR eggNOG; COG0421; Bacteria.
DR OrthoDB; 117774at2; -.
DR Proteomes; UP000012019; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43317:SF12; POLYAMINE AMINOPROPYLTRANSFERASE; 1.
DR PANTHER; PTHR43317; THERMOSPERMINE SYNTHASE ACAULIS5; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|ARBA:ARBA00023115, ECO:0000256|PROSITE-
KW ProRule:PRU00354}; Reference proteome {ECO:0000313|Proteomes:UP000012019};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 1..230
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 146
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 266 AA; 30194 MW; 885A0C1CBBC9B82B CRC64;
MRIYDGVLVH QAISDEGIIE VVDVGDVRSL HFGTHPRQSS MSLKVPYRLE LSYTRAMMAC
LLFCAAPRKV LLIGLGGGSL VKFLLHHLPD CQIEVVEYRE DVIQVAQRYF AVPDDPRLSI
KKADGFAHAS QQHYLGETNY DLILVDAFDH EGMAASVGVQ PFFDACAGIL SKYGIMATNL
WGTDRAGFNL TMQRINRSFD DNSLVLPVED KGNVIAFARH QAFDLTTLRK QRQQIEMMEM
QYQTDLMKSW QILLRQNTTF ISRWFG
//
