ID M7P4R4_PNEMU Unreviewed; 526 AA.
AC M7P4R4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Nucleolar protein 56 {ECO:0000256|ARBA:ARBA00040742};
GN ORFNames=PNEG_02978 {ECO:0000313|EMBL:EMR08810.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR08810.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR08810.1}.
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DR EMBL; AFWA02000014; EMR08810.1; -; Genomic_DNA.
DR RefSeq; XP_007875025.1; XM_007876834.1.
DR AlphaFoldDB; M7P4R4; -.
DR STRING; 1069680.M7P4R4; -.
DR GeneID; 19896665; -.
DR VEuPathDB; FungiDB:PNEG_02978; -.
DR eggNOG; KOG2573; Eukaryota.
DR HOGENOM; CLU_015495_4_0_1; -.
DR OMA; DNYMFAK; -.
DR OrthoDB; 5489581at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF0; NUCLEOLAR PROTEIN 56; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274}.
FT DOMAIN 295..413
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 442..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 60153 MW; 30DF0E5AF8DB2B54 CRC64;
MVDQILAEFA TGYALFEVIQ AEAIGAKLRE VQEASQDLSK FGKFIKLRSF LPYRDAANAL
ENIKDISEGL MNENLKTFLE MNLPKFGKKG RIVLGVSDKN LAGDIRARFK GIECDTSEVT
QDLLRGIRFH SEKLLKQLQP GDLEKAQLGL GHSYSRAKVK FNVNKVDNHI INAIAIMDQL
DKGINTFSMR IREWYGWHMP ELVKFVNDNY QYAKLAIYIG NKTSLSQDNL QDIAAIVNND
PITAQNIINT ARISMGQDMS TVDMENIVIF AQKVVDLVDY RKKLYTYLVN KMNTIAPNLT
KLIGEVIGAR LISHAGSLTN LSKYPASTVQ ILGAEKALFR ALKTKGNTPK YGIIYHSSFI
GRAEQRNKGR ISRFLANKCA IASRIDNFTE IPTTRFGEIL KKQVEERLSF YESGTALTKN
SIAMKQAINL VLSENISQNI SEKDKRNKEK TKEKKKEKDK KKEKDKKKEK DKKKEKKIEK
QEKEKDKVKK EKKKQKKEKE SKEKRSREDE EEIKSSKKRK KENKNK
//
