ID M7P504_PNEMU Unreviewed; 238 AA.
AC M7P504;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=RING-CH-type domain-containing protein {ECO:0000259|PROSITE:PS51292};
GN ORFNames=PNEG_02711 {ECO:0000313|EMBL:EMR08930.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR08930.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR08930.1}.
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DR EMBL; AFWA02000007; EMR08930.1; -; Genomic_DNA.
DR RefSeq; XP_007874736.1; XM_007876545.1.
DR AlphaFoldDB; M7P504; -.
DR GeneID; 19896402; -.
DR VEuPathDB; FungiDB:PNEG_02711; -.
DR eggNOG; KOG3053; Eukaryota.
DR HOGENOM; CLU_045297_0_0_1; -.
DR OMA; CLQSWRH; -.
DR OrthoDB; 2718337at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16495; RING_CH-C4HC3_MARCH; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46347; RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR46347:SF1; RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN; 1.
DR Pfam; PF12906; RINGv; 1.
DR SMART; SM00744; RINGv; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51292; ZF_RING_CH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 90..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..76
FT /note="RING-CH-type"
FT /evidence="ECO:0000259|PROSITE:PS51292"
SQ SEQUENCE 238 AA; 28025 MW; 3221B7829F3052B0 CRC64;
METASREEDE KDIPICRICY GGVEDQSTLG RLISPCRCQG TIKWVHVNCL LQWRIKSKSS
KSYYRCDQCH YEYLFLRPQL SAILVSYPSL LLCTVLVFIG LSFIAGFIVK LIFYFGFEYI
VDFLFYEPIP IPESFVRPRT LWQIFSVIDT THFILGFISL GAIGTIQLLG PIRNYRTLFR
GQRRRHLRHF QDGIMIFYFT GMLKIAWNLY KKIQTWSRYW LEQLGNRILE VGEQPSNT
//
