ID M7PC12_PNEMU Unreviewed; 189 AA.
AC M7PC12;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=DNA polymerase epsilon subunit D {ECO:0000256|ARBA:ARBA00039775};
DE AltName: Full=DNA polymerase II subunit D {ECO:0000256|ARBA:ARBA00042096};
GN ORFNames=PNEG_03456 {ECO:0000313|EMBL:EMR08014.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR08014.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR08014.1}.
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DR EMBL; AFWA02000016; EMR08014.1; -; Genomic_DNA.
DR RefSeq; XP_007875546.1; XM_007877355.1.
DR AlphaFoldDB; M7PC12; -.
DR STRING; 1069680.M7PC12; -.
DR GeneID; 19897143; -.
DR VEuPathDB; FungiDB:PNEG_03456; -.
DR eggNOG; KOG0870; Eukaryota.
DR HOGENOM; CLU_043417_1_1_1; -.
DR OMA; MPRKETY; -.
DR OrthoDB; 1384627at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR PANTHER; PTHR46172; DNA POLYMERASE EPSILON SUBUNIT 3; 1.
DR PANTHER; PTHR46172:SF1; DNA POLYMERASE EPSILON SUBUNIT 3; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958}.
FT DOMAIN 33..97
FT /note="Transcription factor CBF/NF-Y/archaeal histone"
FT /evidence="ECO:0000259|Pfam:PF00808"
SQ SEQUENCE 189 AA; 21559 MW; 307ED879A90DB884 CRC64;
MTNEHDSSNE LHLSPASISS KKKSVTVSID DLNLPRSVVL RLAKKVLPEH TSIQKDAITA
LIRGSSVFIN YLSAAAFDLS KLSSRKVILP SDVLKAMENI EFSSFIPRMT EELELYEEIL
KEKKNIIELH KNSSIFMESK DEHIIKKIKI DDNEILEKTI RSDVNKNNEY DNHTIDGEDY
SKVEEIDKN
//
