ID M7PDP2_PNEMU Unreviewed; 527 AA.
AC M7PDP2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Splicing factor Cactin {ECO:0000256|ARBA:ARBA00034534};
GN ORFNames=PNEG_03065 {ECO:0000313|EMBL:EMR08589.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR08589.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SIMILARITY: Belongs to the CACTIN family.
CC {ECO:0000256|ARBA:ARBA00006895}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR08589.1}.
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DR EMBL; AFWA02000015; EMR08589.1; -; Genomic_DNA.
DR RefSeq; XP_007875121.1; XM_007876930.1.
DR AlphaFoldDB; M7PDP2; -.
DR STRING; 1069680.M7PDP2; -.
DR GeneID; 19896752; -.
DR VEuPathDB; FungiDB:PNEG_03065; -.
DR eggNOG; KOG2370; Eukaryota.
DR HOGENOM; CLU_011759_2_1_1; -.
DR OMA; HIDFWND; -.
DR OrthoDB; 558574at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR InterPro; IPR019134; Cactin_C.
DR InterPro; IPR018816; Cactin_central.
DR PANTHER; PTHR21737:SF4; CACTIN; 1.
DR PANTHER; PTHR21737; POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3; 1.
DR Pfam; PF10312; Cactin_mid; 1.
DR Pfam; PF09732; CactinC_cactus; 1.
DR SMART; SM01050; CactinC_cactus; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011958}.
FT DOMAIN 39..227
FT /note="Splicing factor cactin central"
FT /evidence="ECO:0000259|Pfam:PF10312"
FT DOMAIN 392..527
FT /note="Splicing factor Cactin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09732"
SQ SEQUENCE 527 AA; 62602 MW; 0D6BC5DF9B2A555D CRC64;
MKEHRSRSRS PTTSYSNNKR VKSIGRIRRI PYGPLTEDYK KILVWQSKEG EFILSQAKKR
AELRVQYGRE TPIDILAVHL RIIDKTEDFC EEQPEHAEVV LKDPVVFLET LNLEALEELE
KEINQYLKWE TEEENIEFWR SIDVIRRDQI LKLKSKGHDN GEFRLSRTIE AQVDSLLKGK
TKEELEILGA QIDEKLQGET LIDVDYWEKM KECLIVWKSR VILKELHKKI LHQRREALKN
QQLHEGRMDR EALKNIYNKK ILDPNYCFIK DDKTFIAQVT ELPDIYQETM DPEPLSILEY
EDKKSYRIHE SAYQDQLISD RDRILRSGFV PIKMVKNDIP ISKNLPNTDD ITDDSFSTIT
NVLYEREASK GENDDEELFN VEEEIIQTTP SWADTYRPRK PKFFNRVQTG YDWNRYNQVH
YDANNPPPKV IQGYKFNIFY PDLIDKTKAP TYRIERNKKK NSGQDLFSED ETCLIRFIAG
PPYEDIAFRI IDKDWDYSAK RERGFKSSFD KGVLHLSFQF KKVFYRK
//
